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Accepted for/Published in: JMIR Research Protocols

Date Submitted: May 14, 2025
Date Accepted: Sep 15, 2025

The final, peer-reviewed published version of this preprint can be found here:

Machine Learning in Health Economic Evaluations: Protocol for a Scoping Review

Daghash H, Kernohan A, Brownson-Smith R, Pandey R, Ananthakrishnan A, Cong C, Riccalton V, Meinert E, Sagoo GS

Machine Learning in Health Economic Evaluations: Protocol for a Scoping Review

JMIR Res Protoc 2025;14:e77494

DOI: 10.2196/77494

PMID: 40991936

PMCID: 12508662

Machine Learning in Health Economic Evaluations: A Scoping Review Protocol

  • Hanan Daghash; 
  • Ashleigh Kernohan; 
  • Rosiered Brownson-Smith; 
  • Rohan Pandey; 
  • Ananya Ananthakrishnan; 
  • Cen Cong; 
  • Victoria Riccalton; 
  • Edward Meinert; 
  • Gurdeep S Sagoo

ABSTRACT

Background:

In recent years, the development of Machine Learning (ML) technologies has increased substantially, indicating the potential role of ML in transforming healthcare. However, the integration of ML approaches into health economic evaluations is underexplored and has several challenges.

Objective:

This scoping review aims to explore the applications of ML in health economic evaluations. This review will also seek to identify some potential challenges to the use of ML in health economic evaluations.

Methods:

This review will use PRISMA-ScR methods. The search will be conducted on MEDLINE (Ovid), Embase (Ovid), IEEE Xplore and Cochrane Library. The eligibility criteria of the selection process will be based on the SDMO framework approach (Study types, Data sources, Methods, Outcomes).

Results:

The database search is ongoing. The results will be published in peer-reviewed journals by the end of 2025.

Conclusions:

This review will help to build up the current understanding of how ML applications are integrated in health economics evaluations. This will also explore the potential barriers and challenges on using ML in health economics evaluations. Clinical Trial: osf.io/bgjmr


 Citation

Please cite as:

Daghash H, Kernohan A, Brownson-Smith R, Pandey R, Ananthakrishnan A, Cong C, Riccalton V, Meinert E, Sagoo GS

Machine Learning in Health Economic Evaluations: Protocol for a Scoping Review

JMIR Res Protoc 2025;14:e77494

DOI: 10.2196/77494

PMID: 40991936

PMCID: 12508662

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