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Accepted for/Published in: JMIR Serious Games

Date Submitted: May 8, 2025
Open Peer Review Period: May 12, 2025 - Jul 7, 2025
Date Accepted: Dec 19, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Research Design Processes in Serious Games for Adolescent Mental Health: Systematic Review

Rooij, de ST, Kuipers DA, Prins J, Pierie J

Research Design Processes in Serious Games for Adolescent Mental Health: Systematic Review

JMIR Serious Games 2026;14:e77173

DOI: 10.2196/77173

PMID: 41961995

Research Design Processes in Serious Games for Adolescent Mental Health: Systematic Review.

  • Steven Tijmen Rooij, de; 
  • Derek Albert Kuipers; 
  • J.T. Prins; 
  • J.P.E.N. Pierie

ABSTRACT

Background:

Serious games are increasingly recognized as effective tools for healthcare interventions, particularly for adolescents with behavioral and developmental needs. However, inconsistent design frameworks and limited integration of theoretical concepts challenge their scalability and impact. Understanding how these concepts are applied in serious game design is essential for enhancing their real-world impact.

Objective:

The objective of this systematic review is to examine the current state of the art in the use of serious gaming interventions in healthcare for adolescents with behavioral or developmental issues. The review will focus on elucidating the elements involved in how these games are designed and can contribute to learning. The review is conducted from the theoretical framework perspectives of boundary crossing, transfer and a model of reality.

Methods:

A total of five databases (PubMed, Scopus, ERIC, PsycINFO and EMBASE) were searched for relevant titles and abstracts. The databases were identified as relevant and cover a wide range of published research into health and social science.

Results:

A total of 34 relevant studies were included in the review, which covered a range of serious gaming artefacts with the objective of identifying learning or development opportunities for adolescents with behavioral or developmental issues.

Conclusions:

This review highlights the transformative potential of serious games in healthcare, particularly for individuals with developmental and behavioral needs, by fostering skill acquisition, collaboration, and real-world application. Despite their potential, the development of serious games requires a more structured integration of theoretical frameworks to ensure scalability, replicability, and sustained impact. Future research should prioritize standardized methodologies, longitudinal evaluations, and a focus enhanced collaboration.


 Citation

Please cite as:

Rooij, de ST, Kuipers DA, Prins J, Pierie J

Research Design Processes in Serious Games for Adolescent Mental Health: Systematic Review

JMIR Serious Games 2026;14:e77173

DOI: 10.2196/77173

PMID: 41961995

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© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.