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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: May 8, 2025
Date Accepted: Jun 26, 2026

The final, peer-reviewed published version of this preprint can be found here:

Proximal Effects of a Transdiagnostic, Ecological Momentary Intervention for Enhancing Resilience in Help-Seeking Young People (EMIcompass): Findings From a Secondary Analysis of an Exploratory Randomized Controlled Trial

Gugel J, Paetzold I, Rauschenberg C, Schick A, Hirjak D, Boehnke JR, Boecking B, Reininghaus U

Proximal Effects of a Transdiagnostic, Ecological Momentary Intervention for Enhancing Resilience in Help-Seeking Young People (EMIcompass): Findings From a Secondary Analysis of an Exploratory Randomized Controlled Trial

J Med Internet Res 2026;28:e77150

DOI: 10.2196/77150

PMID: 42691341

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Zooming in: Proximal effects of a transdiagnostic, ecological momentary intervention for enhancing resilience in help-seeking young people (EMIcompass)

  • Jessica Gugel; 
  • Isabell Paetzold; 
  • Christian Rauschenberg; 
  • Anita Schick; 
  • Dusan Hirjak; 
  • Jan Rasmus Boehnke; 
  • Benjamin Boecking; 
  • Ulrich Reininghaus

ABSTRACT

Background:

Ecological momentary interventions (EMIs) offer a promising strategy for targeting putative mechanisms of mental health problems by delivering real-time, tailored intervention components that adapt to person, moment, and context based on data collected using ecological momentary assessment (EMA). However, most research to date focuses on effects on distal outcomes, at the person level, whereas explorations of processes at the micro-level, i.e., proximal effects of EMI components on putative momentary mechanisms and outcomes, remains very limited.

Objective:

This study aimed to explore the proximal effects of completing EMI components on momentary mental health mechanisms and outcomes (i.e., negative affect, stress, stress reactivity) at the subsequent EMA among youth with early mental health problems.

Methods:

EMIcompass is a novel, transdiagnostic, compassion-focused EMI for prevention and early intervention of severe mental health conditions in help-seeking youth. Data were derived from the experimental condition of the EMIcompass exploratory randomized controlled trial, in which youth aged 14-25 with early mental health problems were randomly allocated to intervention + TAU (experimental condition) or TAU only (control condition).

Results:

We found some evidence of proximal effects of EMI interactive task completion on greater reductions in negative affect, stress, and stress reactivity in a small subsample of n=37 participants. The effect sizes of within-subject reductions in momentary negative affect (β = 0.13, z =1.36, 95% CI = −0.06 to 0.31, d = 0.14, stress (β = 0.19, z = 1.44, 95% CI = −0.07 to 0.44, d = 0.14), and stress reactivity (β = 0.15, z = 1.15, 95% CI = -0.11 – 0.42, d = 0.12) were small to moderate but 95% CIs included zero. Further exploratory analyses suggested greater reductions in momentary negative affect for some types of EMI exercises, i.e. “breathing exercises” (β = 0.39, z = 2.12, 95% CI = 0.03 – 0.75, d = 0.36) and “soothing imagery” (β = 0.24, z = 1.27, 95% CI = -0.13 – 0.61, d = 0.22) but not others.

Conclusions:

Our findings illustrate the feasibility of investigating micro-level processes within an EMI framework, but remain equivocal with regard to proximal effects, owing to limited power in this small sample. Further research with larger samples and appropriate study designs is needed to clarify how EMI components impact momentary mental health mechanisms and outcomes. Clinical Trial: This study uses data from the EMIcompass exploratory RCT that was registered in the German Clinical Trials Register (DRKS00017265).


 Citation

Please cite as:

Gugel J, Paetzold I, Rauschenberg C, Schick A, Hirjak D, Boehnke JR, Boecking B, Reininghaus U

Proximal Effects of a Transdiagnostic, Ecological Momentary Intervention for Enhancing Resilience in Help-Seeking Young People (EMIcompass): Findings From a Secondary Analysis of an Exploratory Randomized Controlled Trial

J Med Internet Res 2026;28:e77150

DOI: 10.2196/77150

PMID: 42691341

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