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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Apr 29, 2025
Open Peer Review Period: Apr 30, 2025 - Jun 25, 2025
Date Accepted: Jul 29, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Costs and Cost-Effectiveness at 12 and 24 Months of an Enhanced Web-Based Physical Activity Intervention for Latina Adults: Secondary Analysis of a Randomized Controlled Trial

Larsen B, Pekmezi D, Hartman S, Dunsiger S, Gilmer T, Groessl E, Marcus B

Costs and Cost-Effectiveness at 12 and 24 Months of an Enhanced Web-Based Physical Activity Intervention for Latina Adults: Secondary Analysis of a Randomized Controlled Trial

J Med Internet Res 2025;27:e76739

DOI: 10.2196/76739

PMID: 41289583

PMCID: 12690284

An Enhanced Web-Based Physical Activity Intervention for Latinas: Costs and Cost-Effectiveness at 12- and 24-Months from Pasos Hacia La Salud II

  • Britta Larsen; 
  • Dorothy Pekmezi; 
  • Sheri Hartman; 
  • Shira Dunsiger; 
  • Todd Gilmer; 
  • Erik Groessl; 
  • Bess Marcus

ABSTRACT

Background:

Increasing adherence to physical activity (PA) guidelines could prevent chronic disease morbidity and mortality, save considerable healthcare costs, and reduce health disparities. We previously established the efficacy and cost-effectiveness of a web-based PA intervention for Latina women, which increased PA but few participants met PA guidelines and long-term maintenance was not examined. A new version with enhanced intervention features was found to outperform the original intervention in long-term guideline adherence.

Objective:

to determine the costs and cost-effectiveness of the enhanced multi-technology PA intervention vs. the original web-based intervention in increasing minutes of activity and adherence to guidelines

Methods:

Latina adults (N=195) were randomly assigned to receive a Spanish language individually tailored web-based PA intervention (Original), or the same intervention additional phone calls and interactive text messaging (Enhanced). PA was measured at baseline, 12 months (end of active intervention), and 24 months (end of tapered maintenance) using self-report (7-Day Physical Activity Recall Interview) and ActiGraph accelerometers. Costs were estimated from a payer perspective and included all features needed to deliver the intervention, including staff, materials, and technology. Cost effectiveness was calculated as the cost per additional minute of PA added over the intervention, and the incremental cost effectiveness ratios of each additional person meeting guidelines.

Results:

at 12 months, the costs of delivering the interventions were $16/person/month and $13/person/month in the Enhanced and Original arms, respectively. These costs fell to $14 and $8 at 24 months. At 12 months, each additional minute of self-reported activity in the Enhanced group cost $0.09 vs. $0.11 in Original ($0.19 vs. $0.16 for ActiGraph), with incremental costs of $0.05 per additional minute in Enhanced beyond Original. At the end of maintenance (24 months), costs per additional minute fell to $0.06 and $0.05 ($0.12 vs. $0.10 for ActiGraph), with incremental costs of $0.08 per additional minute in Enhanced ($0.20 for ActiGraph). Costs of meeting PA guidelines at 12 months were $705 vs. $503 in Enhanced vs. Original, and increased to $812 and $601 at 24 months. The ICER for meeting guidelines at 24 months was $1837 (95% CI $730.89-$2673.89) per additional person in the Enhanced vs. Original arm.

Conclusions:

As expected, the Enhanced intervention was more expensive, but yielded better long-term maintenance of activity. Both conditions were low costs relative to other medical interventions. The Enhanced intervention may be preferable in high risk populations, where more investment in meeting guidelines could yield more cost savings. Clinical Trial: NCT03491592


 Citation

Please cite as:

Larsen B, Pekmezi D, Hartman S, Dunsiger S, Gilmer T, Groessl E, Marcus B

Costs and Cost-Effectiveness at 12 and 24 Months of an Enhanced Web-Based Physical Activity Intervention for Latina Adults: Secondary Analysis of a Randomized Controlled Trial

J Med Internet Res 2025;27:e76739

DOI: 10.2196/76739

PMID: 41289583

PMCID: 12690284

Per the author's request the PDF is not available.

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