JMIR Publications

ABSTRACT

Background:

When the teeth's attachment system is lost due to periodontal disorders, especially periodontitis, osseous abnormalities, extensive periodontal pockets, and tooth mobility result. Patients experience both practical and aesthetic issues as a result of these impairments. Restoring the periodontal attachment, which includes the cementum, periodontal ligament, and alveolar bone, is the primary objective of periodontal regeneration therapy. Regenerative therapy approaches can be very helpful for infrabony deficiencies, one of the prevalent forms of bone loss brought on by periodontitis.

Objective:

1. To evaluate the effectiveness of AmnioGuard in combination with Nova Bone putty in terms of gain in clinical attachment level(CAL), reduction in probing pocket depth (PPD) and radiographic bone fill in infrabony defects at 6 months post surgery. 2. To evaluate the effectiveness of A-PRF in combination with Nova Bone putty in terms of gain in clinical attachment level, reduction in probing pocket depth and radiographic bone filled 6 months post surgery. 3. To compare the effectiveness of AmnioGuard and A-PRF in combination with Nova Bone putty at 6 months post surgery and bone fill as seen on CBCT.

Methods:

Twenty-four infrabony defects in individuals with good systemic health will be treated with NovaBone putty in combination with Amnioguard (Group-A) and NovaBone putty in combination with autologous PRF (Group-B). Clinical and radiographic features will be evaluated before surgery and six months following the procedure. The final data is subjected to statistical analysis. There will be noticeable improvement in both groups' Plaque index, Papillary bleeding index, Periodontal probing depth, and Clinical attachment loss, following periodontal therapy in both groups at 6 months period. On intergroup comparison Amnioguard membrane with NovaBone Putty will show better outcome than A-PRF Membrane with NovaBone Putty.

Results:

All the clinical measurements will be recorded at the baseline and 3 months. Plaque index, which indicates the degree of full mouth supragingival plaque accumulation, will be used to assess the patient's dental hygiene state and will be measured at the one-month follow-up. Although a substantial difference between the groups is not anticipated, Amnioguard + Novabone Putty would show improvement in clinical outcomes, such as CAL and PPD.

Conclusions:

Within the constraints of the present study, it will be concluded that Amnioguard membrane with NovaBone Putty will provide additional benefits in the management of chronic periodontitis by promoting better healing and clinical outcomes.