Currently submitted to: JMIR Preprints
Date Submitted: Apr 1, 2025
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The Effect of Mobile Phone and Home Visit on Childhood Vaccination Uptake in Rural Communities of Bayelsa State Nigeria. A Pragmatic Cluster Randomized Control Trial
ABSTRACT
Background:
Immunization is a critical public health intervention for preventing vaccine-preventable diseases (VPDs) and achieving herd immunity. However, suboptimal vaccination coverage remains a challenge, particularly in rural and underserved areas. Missed appointments due to forgetfulness and logistical barriers contribute significantly to low immunization rates. This study evaluates the impact of mobile phone (MP) reminders and home visits (HV) on childhood immunization completion rates in Bayelsa State, Nigeria.
Objective:
The study aimed to assess the effectiveness of MP reminders and HV outreach in improving vaccination coverage among children under two years of age.
Methods:
A pragmatic cluster randomized controlled trial was conducted in rural communities of Bayelsa State, Nigeria. A total of 384 participants were randomly assigned to three study arms: control (no intervention), MP reminders, and HV outreach (128 per arm). A multi-stage sampling technique was employed, and data were collected using a semi-structured WHO SAGE survey tool. Statistical analyses were performed using SPSS v25, with chi-square (χ²) tests used to compare categorical variables. Statistical significance was set at p ≤ 0.05, with effect sizes reported.
Results:
The study revealed significant differences in immunization completion rates across study groups: control (46.1%, 59/128), MP reminders (59.4%, 76/128), and HV outreach (63.3%, 81/128). Both interventions were effective in improving vaccination uptake, with a statistically significant difference (p = 0.015) and a moderate effect size (0.257). However, HV outreach demonstrated the highest completion rate, suggesting its greater effectiveness in overcoming access and engagement barriers.
Conclusions:
Integrating MP reminders and HV outreach into routine immunization programs can significantly improve childhood vaccination coverage. HV, in particular, addresses accessibility challenges and enhances community trust, making it a preferred strategy for increasing immunization rates. To optimize immunization coverage, policymakers should implement a hybrid approach, combining MP reminders with HV outreach, particularly in rural and underserved areas. Strengthening community-based health worker engagement and leveraging digital health innovations will further enhance vaccination efforts. Improved immunization coverage through these interventions reduces the risk of VPD outbreaks, enhances herd immunity, and contributes to achieving global vaccination targets. By addressing barriers to vaccine access and adherence, these strategies offer scalable, cost-effective solutions for improving child health outcomes. This trial provides robust evidence on the effectiveness of digital and community-based interventions for improving vaccination coverage. By comparing MP reminders and HV outreach, the study offers practical insights for health policymakers and program implementers. The findings contribute to global immunization research by highlighting scalable, low-cost solutions that can be adapted in resource-limited settings to strengthen immunization programs and reduce childhood morbidity and mortality.
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