Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Mar 18, 2025
Date Accepted: Feb 6, 2026

The final, peer-reviewed published version of this preprint can be found here:

Comparative Analysis of Prescriptions and Pharmacy Services in Internet-Based Psychiatric Hospital During and After the COVID-19 Pandemic: Retrospective Cross-Sectional Observational Study

Tan Y, Deng G, Xia H, Shang D, Wen Y, Hu J

Comparative Analysis of Prescriptions and Pharmacy Services in Internet-Based Psychiatric Hospital During and After the COVID-19 Pandemic: Retrospective Cross-Sectional Observational Study

J Med Internet Res 2026;28:e74059

DOI: 10.2196/74059

PMID: 41780924

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

A Comparative Study of Pharmacy Services and Prescription Analysis in Internet-based Psychiatric Hospital During and After the COVID-19 Pandemic

  • Yaqian Tan; 
  • Guowei Deng; 
  • Hui Xia; 
  • Dewei Shang; 
  • Yuguan Wen; 
  • Jinqing Hu

ABSTRACT

Background:

The COVID-19 pandemic has profoundly affected the mental health care system globally, and patients with mental disorders were more vulnerable to various challenges caused by pandemic-related quarantine measures. To ensure continuous and accessible pharmaceutical services for those patients, the Affiliated Brain Hospital, Guangzhou Medical University has implemented an internet-based hospital platform to offer remote pharmaceutical services.

Objective:

This study aimed to analyze the characteristics and trends of internet-based psychiatric hospital prescriptions during and after the COVID-19 pandemic.

Methods:

The electronic prescriptions from November 10th 2020 to December 31st 2023 were collected from the internet-based hospital. The characteristic analysis included factors such as gender, age, primary diagnosis, medications, audit time, approval rate, and the number of prescriptions per month.

Results:

In this study, a total of 17,330 electronic prescriptions were collected from the internet-based hospital. During the pandemic phase, there were 11,812 prescriptions, with a male-to-female ratio of 1:1.62 and 47.46% of patients aged 18-40. Comparatively, in the post-pandemic phase, among 5,518 prescriptions, the gender ratio shifted to 1:1.76, the proportion of patients aged 18-40 increased marginally to 48.15%. Regarding primary diagnosis, during the pandemic phase, the top three diagnoses were depressive disorder (n=3,539, 29.96%), schizophrenia (n=2,095, 17.74%), and bipolar disorder (n=1,632, 13.82%). In the post-pandemic period, the top three diagnosis changed to depressive disorder (n=2,094, 37.95%), mood disorder (n=1,191, 21.58%), and schizophrenia (n=607, 11.00%). Quetiapine, lithium carbonate, and escitalopram remained the most prescribed medications throughout both periods. Prescription processing times showed notable variations. During the pandemic, 50.79% of prescriptions were audited within 5 minutes, compared to 18.09% post-pandemic. Conversely, prescriptions audited within 1-12 hours increased from 12.41% to 36.81% between periods. Rates of pharmacist approval and Physician double-check requirements demonstrated significant improvements. The proportion of prescriptions approved by pharmacists increased from 83.34% to 96.54%, while the proportion of prescriptions double-check by doctors decreased from 16.47% to 3.41%. Internet-based hospital utilization revealed dramatic growth. Initial operations yielded only 76 prescriptions (0.44%) in the first seven months, which surged to 3,427 (19.77%) during the month of suspended outpatient services. After the pandemic prescription volumes stabilized at approximately 460 per month.

Conclusions:

The psychiatric hospital demonstrated the online medication services provided by internet-based hospitals were increasingly embraced by patients and evolved into routine healthcare solutions. This study revealed the characteristics and trends of electronic prescriptions in internet-based psychiatric hospitals during and after the COVID-19 pandemic, and may provide reference for public crisis in the future.


 Citation

Please cite as:

Tan Y, Deng G, Xia H, Shang D, Wen Y, Hu J

Comparative Analysis of Prescriptions and Pharmacy Services in Internet-Based Psychiatric Hospital During and After the COVID-19 Pandemic: Retrospective Cross-Sectional Observational Study

J Med Internet Res 2026;28:e74059

DOI: 10.2196/74059

PMID: 41780924

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.