Accepted for/Published in: JMIR Formative Research
Date Submitted: Mar 12, 2025
Open Peer Review Period: Mar 25, 2025 - May 20, 2025
Date Accepted: May 22, 2025
(closed for review but you can still tweet)
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
A Novel Framework of Multi-Domain Behavioral Change Agents to Coach Chronic Disease Patients Towards Achieving Personalized Health Goals
ABSTRACT
Background:
Unhealthy lifestyle behaviors have been identified as a major cause of numerous health issues with a steady global increase. Addressing this challenge requires comprehensive behavioral changes to promote sustainable healthier lifestyle adoption. However, despite the prevalent need, cost effective and successful health-related behavior change virtual coaching, remain scarce.
Objective:
This paper presents a holistic framework for designing, modeling and executing behavioral change strategies, through a multi-agent reasoning system that selects optimal virtual coaching techniques based on individual assessments and integrates data-driven decision making.
Methods:
Behavioral change theories have been explored to design a multi-agent system that aims to achieve sustainable lifestyle changes. This system selects behavior change techniques (BCTs) based on individual user assessments, prioritizing those with the strongest impact on key behavioral components. The framework incorporates evidence-based practices stemming from behavioral change science and integrates them into Healthentia Behavioral Change Coaching (BCC) scheme. Healthentia, a certified software as medical device (SaMD), implements this framework specifically for chronic disease management, serving as an eHealth solution advancing decentralized care by enabling remote monitoring, data-driven content selection and personalized virtual coaching that adjusts to patient progress and engagement patterns.
Results:
This paper explores the application of the Healthentia BCC scheme in Type 2 diabetes patients and presents preliminary results that show improvements in weight (-2.53 kg, p=0.0352), BMI (-0.925 kg/m², p=0.0348), and trends toward improvement in fasting glucose and sleep goal fulfillment. The positive outcomes are at least partly attributed to the personalized delivery of content, 85% of which is well-received by the patients.
Conclusions:
Our study of this multi-agent system, tested through simulated patient behavior and a preliminary, limited Type 2 diabetes patient behavior observations, promises improved health outcomes using personalized virtual coaching strategies. Future directions include optimization of the multi-agent selection process, a further exploration of the Type 2 diabetes program and an in-depth evaluation of its results, including HbA1c measurements, and an applications’ expansion to other chronic conditions.
Citation
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.