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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Mar 2, 2025
Date Accepted: May 5, 2025

The final, peer-reviewed published version of this preprint can be found here:

Activity-Based Interventions to Increase Independence After Stroke In the Hospital Setting: Protocol for a Systematic Review

Grant T, Jolliffe L, Wales K, Schneider E, Drummond AE, Lannin NA

Activity-Based Interventions to Increase Independence After Stroke In the Hospital Setting: Protocol for a Systematic Review

JMIR Res Protoc 2025;14:e73133

DOI: 10.2196/73133

PMID: 40627860

PMCID: 12284451

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Activity-based interventions to increase independence after stroke within the hospital setting: Protocol for a systematic review

  • Tayla Grant; 
  • Laura Jolliffe; 
  • Kylie Wales; 
  • Emma Schneider; 
  • Avril E. Drummond; 
  • Natasha A. Lannin

ABSTRACT

Background:

Stroke is a leading cause of disability, commonly resulting in difficulty completing basic and instrumental activities of daily living. Rehabilitation is recommended to improve functional performance, however it remains unknown whether early (hospital-based) intervention is effective nor the intervention components that should be delivered.

Objective:

We propose a systematic review to summarize the evidence for the effectiveness of activity-based interventions, led by occupational therapists, for improving performance of basic activities of daily living (b-ADL) or simple cognitive instrumental activities of daily living (C-IADL) by adults with stroke. Reviewing simple C-IADLs as opposed to instrumental activities of daily living will allow us to review interventions for activities with similar executive functioning demands. By identifying effective interventions, we aim to improve outcomes for stroke survivors by maximizing independence during hospitalization.

Methods:

Searches will be conducted in MEDLINE, CINAHL, EMBASE and Cochrane Controlled Register of Trials. We will include randomized controlled trials and quasi-randomized controlled trials which include adult stroke survivors and which are testing interventions (delivered in the hospital setting) that aimed to improve or promote independence in b-ADL or C-IADL activities. Two reviewers will independently screen full text articles and one reviewer will extract data, with a second reviewer providing confirmation. The PEDro Scale will be used to assess methodological quality of studies. Cochran Q test will assess heterogeneity among studies, then where appropriate, meta-analysis will be performed. Measures of outcome may include global rating of function (such as the Functional Independence Measure, FIMâ„¢) or specific task performance assessments (such as the Nottingham Dressing Assessment).

Results:

Results will be presented based on subgroup analyses where able, including activity type (activity or occupation level), time post-stroke (within or greater than 1 week), and delivery of intervention (group or individualized).

Conclusions:

This systematic review will address the current gap in the literature regarding activity-based interventions for stroke survivors, within the inpatient setting, and provide clinical guidance on the most effective methods, if any, for improving independence early after stroke. Clinical Trial: PROSPERO, https://www.crd.york.ac.uk/prospero/ (Registration ID: CRD42024562195)


 Citation

Please cite as:

Grant T, Jolliffe L, Wales K, Schneider E, Drummond AE, Lannin NA

Activity-Based Interventions to Increase Independence After Stroke In the Hospital Setting: Protocol for a Systematic Review

JMIR Res Protoc 2025;14:e73133

DOI: 10.2196/73133

PMID: 40627860

PMCID: 12284451

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