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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Feb 23, 2025
Date Accepted: Dec 29, 2025

The final, peer-reviewed published version of this preprint can be found here:

Prevalence and Factors Associated With Acute Stress Disorder Among Adults Ever Infected With COVID-19 During the Ending Phase of the Pandemic in 7 Chinese Cities: Cross-Sectional Study

Yang Z, Yu Y, Lu H, Wang X, Xu Y, Ying J, Wen X, Luo L, Wang M, Liu M, Geng X, Zhao X, He B, Liu T, Maimaitijiang R, Gu J, Lau J

Prevalence and Factors Associated With Acute Stress Disorder Among Adults Ever Infected With COVID-19 During the Ending Phase of the Pandemic in 7 Chinese Cities: Cross-Sectional Study

JMIR Public Health Surveill 2026;12:e73002

DOI: 10.2196/73002

PMID: 41812140

Prevalence and factors associated with acute stress disorder among adults ever infected with COVID-19 during the ending phase of the pandemic in China: a cross-sectional study in seven Chinese cities

  • Ziying Yang; 
  • Yanqiu Yu; 
  • Hui Lu; 
  • Xu Wang; 
  • Yong Xu; 
  • Junqiang Ying; 
  • Xianying Wen; 
  • Lei Luo; 
  • Meng Wang; 
  • Muwen Liu; 
  • Xingyi Geng; 
  • Xuchong Zhao; 
  • Biyu He; 
  • Tao Liu; 
  • Remina Maimaitijiang; 
  • Jing Gu; 
  • Joseph Lau

ABSTRACT

Background:

Acute stress disorder (ASD) among people ever infected with COVID-19 (PEIC) is prevalent and may lead to post-trauma stress disorder. Soon after China relaxed her COVID-19 control measures in November/December 2022, the infection rate surged rapidly, creating huge uncertainty and stressful situations.

Objective:

Little is known about situations regarding ASD at the ending phase of the pandemic. Potential personal cognitive/emotional factors and environmental factors of ASD were investigated in this study.

Methods:

A cross-sectional study was conducted among 5,545 PEIC aged 18-60 years from December 27, 2022 to January 9, 2023 living in seven cities of China. The 5-item Chinese version of the Primary Care PTSD Screen was used to assess ASD. Multiple logistic regression analyses were performed to identify factors of ASD.

Results:

The prevalence of ASD was 21.2%. Adjusted for the background variables, significant personal cognitive risk factors (COVID-19 infection severity, perceived high reinfection risk and perceived weak natural immunity acquired), emotional risk factors (worry about the long-term physical harms, and panic about infection of elderly or young family members), and significant environmental risk factors (difficulties in getting information and medical supplies, having unvaccinated old/young family members, and having significant others suffering from severe COVID-19 symptoms) were identified.

Conclusions:

The prevalence of ASD among PEIC was noticeable. It is warranted to identify those at high risk of developing ASD and provide them with care and early interventions to prevent deterioration. Such programs may consider modifying the risk factors found in this study.


 Citation

Please cite as:

Yang Z, Yu Y, Lu H, Wang X, Xu Y, Ying J, Wen X, Luo L, Wang M, Liu M, Geng X, Zhao X, He B, Liu T, Maimaitijiang R, Gu J, Lau J

Prevalence and Factors Associated With Acute Stress Disorder Among Adults Ever Infected With COVID-19 During the Ending Phase of the Pandemic in 7 Chinese Cities: Cross-Sectional Study

JMIR Public Health Surveill 2026;12:e73002

DOI: 10.2196/73002

PMID: 41812140

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