Accepted for/Published in: JMIR Research Protocols
Date Submitted: Feb 11, 2025
Date Accepted: Oct 1, 2025
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Emerging Interventions to Improve Health Outcomes for People Aging with HIV: Protocol for an Implementation Science Evaluation
ABSTRACT
Background:
In 2022, 54% of people with HIV were aged 50 and older, yet clinical care for HIV often falls short of comprehensively integrating care for aging-related conditions. In response, the Health Resources and Services Administration’s HIV/AIDS Bureau’s Ryan White HIV/AIDS Program (RWHAP) funded a new initiative comprised of 10 demonstration sites to test emerging interventions to support persons aging with HIV, as well as a capacity-building provider and an evaluation provider. NORC at the University of Chicago received the award for the evaluation provider.
Objective:
The purpose of this article is to describe application of the HRSA HAB Implementation Science Framework to a multi-site evaluation, evaluation protocol, technical assistance to support evaluation, and the initiative’s dissemination plan.
Methods:
Using a theory-based approach, NORC developed a mixed-methods evaluation plan using an implementation science Hybrid Study Type 2 with two main aims: 1) describe implementation outcomes, and 2) assess client-level outcomes. Implementation outcomes were assessed at an organizational-level using tools including a survey of site characteristics, key informant interviews, documentation of monthly monitoring calls, and costs. Client-level outcomes were assessed through a survey and medical chart abstraction tool. NORC also collects data on sites’ engagement with the capacity-building provider and their satisfaction with services provided.
Results:
Organizational-level data collection began upon Institutional Review Board (IRB) approval on April 6, 2023. All sites were enrolling clients into the intervention and evaluation by September 2023. Analysis of baseline results is currently underway, and comprehensive findings are expected by late 2025.
Conclusions:
To our knowledge, this is the first national study to evaluate emerging interventions for persons aging with HIV using implementation science. The findings will build the evidence base for advancing HIV clinical care to meet the needs of an aging population.
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