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Accepted for/Published in: JMIR Dermatology

Date Submitted: Feb 8, 2025
Date Accepted: Aug 26, 2025

The final, peer-reviewed published version of this preprint can be found here:

Image Generation of Common Dermatological Diagnoses by Artificial Intelligence: Evaluation Study of the Potential for Education and Training Purposes

Kooper-Johnson S, Lim S, Aldhalaan J, Cobos G, Kodumudi V, Loo DS, Mervis J, Petrillo M, Robinson SN, Nguyen BM

Image Generation of Common Dermatological Diagnoses by Artificial Intelligence: Evaluation Study of the Potential for Education and Training Purposes

JMIR Dermatol 2025;8:e72371

DOI: 10.2196/72371

PMID: 41401374

PMCID: 12707691

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Image Generation of Common Dermatological Diagnoses by Artificial Intelligence; Evaluation of the Potential for Education and Training Purposes

  • Sarah Kooper-Johnson; 
  • Subin Lim; 
  • Jumana Aldhalaan; 
  • Gabriela Cobos; 
  • Vijay Kodumudi; 
  • Daniel S Loo; 
  • Joshua Mervis; 
  • Madalyn Petrillo; 
  • Sarah N Robinson; 
  • Bichchau Michelle Nguyen

ABSTRACT

The integration of artificial intelligence (AI) into dermatology holds promise for education and diagnostic purposes, particularly through image generation, which has not been well studied. Assess whether AI image generation software can generate accurate images of classic dermatological conditions and whether they are recognizable as computer-generated. Images of ten dermatologic conditions were generated from DALLE-2 and DALLE-3 programs. These images were randomized amongst clinical photographs and distributed to dermatology residents and attending physicians. Participants were instructed to: (1) identify AI-generated images and (2) provide their diagnosis. AI-generated images were detected as computer-generated in 70.8% of cases. Correct diagnoses were made based on all AI images 40.83% of the time. This was significantly lower than the 72.0% recognition rate for clinical photographs (p<0.001). DALLE-2 images were diagnosed correctly less frequently (25.0%) than DALLE-3 images (56.6%) (p<0.001). AI generated images of common dermatological conditions are becoming more accurate. This holds great implications for education but should be used with caution as further research is needed with more advanced, specific, and inclusive training data. Limitations include the use of AI image generators created by a single parent company as well as the use of a limited set of diagnoses.


 Citation

Please cite as:

Kooper-Johnson S, Lim S, Aldhalaan J, Cobos G, Kodumudi V, Loo DS, Mervis J, Petrillo M, Robinson SN, Nguyen BM

Image Generation of Common Dermatological Diagnoses by Artificial Intelligence: Evaluation Study of the Potential for Education and Training Purposes

JMIR Dermatol 2025;8:e72371

DOI: 10.2196/72371

PMID: 41401374

PMCID: 12707691

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