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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Feb 6, 2025
Date Accepted: May 27, 2025

The final, peer-reviewed published version of this preprint can be found here:

Innovative Integration of 4D Cardiovascular Reconstruction and Hologram: Framework Development of a New Visualization Tool for Coronary Artery Bypass Grafting Planning

Wang S, Ren T, Cheng N, Zhang L, Wang R

Innovative Integration of 4D Cardiovascular Reconstruction and Hologram: Framework Development of a New Visualization Tool for Coronary Artery Bypass Grafting Planning

JMIR Med Inform 2025;13:e72237

DOI: 10.2196/72237

PMID: 41027031

PMCID: 12483336

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Innovative Integration of 4D Cardiovascular Reconstruction and Hologram: A New Visualization Tool for CABG Planning

  • Shuo Wang; 
  • Tong Ren; 
  • Nan Cheng; 
  • Li Zhang; 
  • Rong Wang

ABSTRACT

Background:

Coronary artery bypass grafting (CABG) planning requires advanced spatial visualization and consideration of factors such as the depth of coronary arteries in the subepicardium, calcification, and pericardial adhesions.

Objective:

This study aimed to fulfill these needs by reconstructing a dynamic cardiovascular model, display it as a naked-eye hologram, and assess the feasibility of this novel visualization tool.

Methods:

Using preoperative 4-dimensional cardiac computed tomography angiography (4D-CCTA) data from 14 patients undergoing CABG, dynamic reconstructions of the heart chambers, epicardial adipose tissue (EAT), and coronary arteries were created to reflect their spatial location, coronary stenosis and calcification, coronary depth in EAT, and pericardial adhesions. Dynamic cardiovascular holograms were generated and displayed on the Looking GlassĀ® platform.13 cardiac surgeons retrospectively assessed the performance of the holographic visualization tool by using a Likert scale. A surgeon visually scored pericardial adhesions in the holograms of all 21 patients (including other 7 patients undergoing secondary cardiac surgery) and compared the scores with the actual intraoperative finding.

Results:

Thirteen cardiac surgeons rated the visualization tool highly due to its impressive display and good correlation with actual intraoperative situation. Meanwhile, the hologram-based pericardial adhesion score was correlated with the pericardial adhesion condition score at the operation (correlation coefficient: r = 0.786, P < 0.001).

Conclusions:

This study delineates the structural framework of a visualization tool designed for the preoperative planning of CABG procedures, generates high-quality, clinically relevant, dynamic holograms by employing genuine volumetric data from patients. The feedback from clinicians is very positive, verifying its feasibility in preoperative planning.


 Citation

Please cite as:

Wang S, Ren T, Cheng N, Zhang L, Wang R

Innovative Integration of 4D Cardiovascular Reconstruction and Hologram: Framework Development of a New Visualization Tool for Coronary Artery Bypass Grafting Planning

JMIR Med Inform 2025;13:e72237

DOI: 10.2196/72237

PMID: 41027031

PMCID: 12483336

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