Accepted for/Published in: JMIR Research Protocols
Date Submitted: Dec 31, 2024
Date Accepted: Mar 30, 2025
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
A Hybrid Effectiveness-Implementation Trial of an Intervention for Justice-Involved Homeless Veterans with Co-Occurring Substance Use and Mental Health Disorders: A Study Protocol
ABSTRACT
Background:
US Veterans Affairs (VA) Mental Health Residential Rehabilitation Treatment Programs (MH RRTP) provide residential care for veterans experiencing homelessness. However, those with co-occurring mental health and substance use disorders (COD) and criminal legal involvement require additional interventions to address risk factors for recidivism.
Objective:
This study aims to evaluate (1) whether MISSION-CJ lowers criminal recidivism and health-related outcomes; (2) whether the effects of MISSION-CJ on these outcomes are mediated by several recidivism risk and protective factors; and (3) qualitatively assess the implementation of MISSION-CJ using the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework.
Methods:
In a Hybrid Type 1 randomized control trial to test the effectiveness and implementation of MISSION-CJ, a multicomponent intervention for COD, veterans participating in MH RRTP (n = 226) will be randomized to enhanced usual care or MISSION-CJ.
Results:
The findings from this trial and qualitative evaluation will be available by 2026.
Conclusions:
If effective, implementation of MISSION-CJ alongside MH RRTP may be advantageous to address risk factors to address recidivism. Clinical Trial: ClinicalTrials.gov NCT04523337
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