Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Research Protocols

Date Submitted: Dec 6, 2024
Date Accepted: Jun 12, 2025

The final, peer-reviewed published version of this preprint can be found here:

Hydrogen-Rich Water Consumption for Acute and Residual Fatigue After Simulated Football Matches: Protocol for a Randomized, Double-Blinded, Placebo-Controlled, Parallel Trial

Hruby M, Hulka K

Hydrogen-Rich Water Consumption for Acute and Residual Fatigue After Simulated Football Matches: Protocol for a Randomized, Double-Blinded, Placebo-Controlled, Parallel Trial

JMIR Res Protoc 2025;14:e69744

DOI: 10.2196/69744

PMID: 40694834

PMCID: 12326158

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

The impact of hydrogen-rich water consumption to acute and residual fatigue after simulated football match: Study protocol for randomized, double blinded, placebo-controlled parallel trial

  • Michal Hruby; 
  • Karel Hulka

ABSTRACT

Background:

IFootball matches induce acute and residual fatigue, impairing neuromuscular, metabolic, and perceptual performance. Hydrogen-rich water (HRW) is a novel intervention with antifatigue and antioxidative properties.

Objective:

This study will investigate the effects of pre-exercise HRW administration versus placebo on performance, biochemical markers, and perceptual measures of fatigue during a 72-hour recovery after a simulated football match.

Methods:

Utilizing a randomized, double-blinded, placebo-controlled, parallel design, elite junior football players underwent assessments of repeated sprint ability, countermovement jump performance, and biochemical indicators (e.g., creatine kinase levels). Testing will be conducted immediately post-match and at 24-, 36-, and 72-hour intervals. Pre- and post-exercise HRW/placebo was administered under standardized conditions.

Results:

This study will assess the influence of molecular hydrogen to acute fatigue manifestation and recovery quality during 72-hour after simulated football match. We expect recruitment to begin during the spring of 2025, data analysis in the summer of 2025, and results by the end of 2025.

Conclusions:

The possible positive effect of molecular hydrogen would speed up the players' readiness to train after the match. Clinical Trial: This in not clinical study.


 Citation

Please cite as:

Hruby M, Hulka K

Hydrogen-Rich Water Consumption for Acute and Residual Fatigue After Simulated Football Matches: Protocol for a Randomized, Double-Blinded, Placebo-Controlled, Parallel Trial

JMIR Res Protoc 2025;14:e69744

DOI: 10.2196/69744

PMID: 40694834

PMCID: 12326158

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.