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Accepted for/Published in: JMIR Cancer

Date Submitted: Dec 10, 2024
Date Accepted: Nov 17, 2025

The final, peer-reviewed published version of this preprint can be found here:

Evaluation of the ALIBIRD mHealth Platform for Care of Patients With Lung Cancer: Prospective Pilot Study

Iniesta-Chamorro JM, Sereno M, Garrido-Rubiales B, Villarino Sanz M, Espinosa-Salinas I, Falagán S, Rubio G, Moreno-Rubio J, Tabarés B, Martín Y, Hernández de Córdoba I, Morales M, Molinero N, Moreno-Arribas MV, Reglero G, Ramírez de Molina A, Gómez EJ, Casado E

Evaluation of the ALIBIRD mHealth Platform for Care of Patients With Lung Cancer: Prospective Pilot Study

JMIR Cancer 2026;12:e69525

DOI: 10.2196/69525

PMID: 41671557

PMCID: 12893646

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Evaluation of the ALIBIRD mHealth Platform for Patient Monitoring in Lung Cancer: Prospective Interventional Study

  • Jose M. Iniesta-Chamorro; 
  • Maria Sereno; 
  • Beatriz Garrido-Rubiales; 
  • Marta Villarino Sanz; 
  • Isabel Espinosa-Salinas; 
  • Sandra Falagán; 
  • Gustavo Rubio; 
  • Juan Moreno-Rubio; 
  • Beatriz Tabarés; 
  • Yolanda Martín; 
  • Irene Hernández de Córdoba; 
  • Maria Morales; 
  • Natalia Molinero; 
  • M. Victoria Moreno-Arribas; 
  • Guillermo Reglero; 
  • Ana Ramírez de Molina; 
  • Enrique J. Gómez; 
  • Enrique Casado

ABSTRACT

Background:

Mobile Health (mHealth) represents a promising instrument for optimizing symptom management and important lifestyle strategies that enhance self-care and the quality of healthcare for cancer patients. The ALIBIRD mHealth is a digital health solution specifically designed for the telemonitoring of oncology patients, fostering patient empowerment and supporting clinical decision-making.

Objective:

The primary objective of this study was to evaluate the patient experience with the ALIBIRD platform. Additionally, the study aimed to assess clinical outcomes, particularly in symptom management, nutritional status, and lifestyle, using patient-reported outcome measures.

Methods:

The evaluation of the mHealth platform was conducted over a 30-week period involving patients with advanced lung cancer who were undergoing active treatment. Through a mobile application, patients reported their symptoms and lifestyle data while receiving personalized recommendations, which included nutrigenetic and microbiota reports. Clinicians monitored patient data remotely using a web-based tool and executed various clinical interventions, including phone calls, therapeutic adjustments, referrals, and appointment rescheduling.

Results:

Out of 20 patients recruited for the study, 14 completed the intervention. The System Usability Scale yielded a score of 90, indicating high levels of patient satisfaction. The ALIBIRD platform collected and processed 3,589 patient-reported outcomes related to physical activity, 3,468 related to sleep, 679 on-demand symptom entries, and 1,524 completed questionnaires. Clinically, 143 alerts were resolved within an average of 2.05 days, resulting in two referrals to emergency rooms and two early detections of disease progressions. Furthermore, over 2,100 personalized recommendations contributed to a 21% increase in adherence to the Mediterranean diet and a 14.28% increase in moderate physical activity.

Conclusions:

The evaluation of the ALIBIRD implementation yielded promising results in that it facilitated the adoption of healthier life-style habits while enhancing health self-management among oncology patients. The ALIBIRD mHealth platform emerges as an effective digital health tool that enables closer monitoring of patients and thereby more informed clinical decision-making. Clinical Trial: ClinicalTrials.gov NCT05770869


 Citation

Please cite as:

Iniesta-Chamorro JM, Sereno M, Garrido-Rubiales B, Villarino Sanz M, Espinosa-Salinas I, Falagán S, Rubio G, Moreno-Rubio J, Tabarés B, Martín Y, Hernández de Córdoba I, Morales M, Molinero N, Moreno-Arribas MV, Reglero G, Ramírez de Molina A, Gómez EJ, Casado E

Evaluation of the ALIBIRD mHealth Platform for Care of Patients With Lung Cancer: Prospective Pilot Study

JMIR Cancer 2026;12:e69525

DOI: 10.2196/69525

PMID: 41671557

PMCID: 12893646

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