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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Nov 7, 2024
Open Peer Review Period: Nov 7, 2024 - Jan 2, 2025
Date Accepted: Jan 5, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Mpox Prevention Self-Efficacy and Associated Factors Among Men Who Have Sex With Men in China: Large Cross-Sectional Study

Cai Y, Gao Q, Liu S, Baier M, Xu H, Zhang J, Xu G, Hu F, Wang Y

Mpox Prevention Self-Efficacy and Associated Factors Among Men Who Have Sex With Men in China: Large Cross-Sectional Study

JMIR Public Health Surveill 2025;11:e68400

DOI: 10.2196/68400

PMID: 40020043

PMCID: 11887935

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Mpox prevention self-efficacy and associated factors among men who have sex with men in China: a large cross-sectional survey

  • Yong Cai; 
  • Quyige Gao; 
  • Shangbin Liu; 
  • MUZAI Baier; 
  • Huifang Xu; 
  • Jiechen Zhang; 
  • Gang Xu; 
  • Fan Hu; 
  • Ying Wang

ABSTRACT

Background:

Self-efficacy in mpox prevention plays a pivotal role in promoting preventive behaviors by fostering a sense of control and motivation, especially among men who have sex with men (MSM), the population most affected by mpox in many countries.

Objective:

This study aims to assess the mpox prevention self-efficacy among MSM in China and identify factors influencing it, using a validated Mpox Prevention Self-Efficacy Scale.

Methods:

From November 2023 to March 2024, a nationwide cross-sectional study was conducted across six geographic regions in China using a snowball sampling method. The Mpox Prevention Self-Efficacy Scale was assessed for reliability and validity. Univariate and multivariate logistic regression were employed to examine factors associated with mpox prevention self-efficacy among MSM.

Results:

Among the 2,403 participants, the median mpox prevention self-efficacy score was 23.00 (IQR = 5.00). The Mpox Prevention Self-Efficacy Scale demonstrated good internal consistency (α > 0.80) and a strong model fit (χ² (N = 1,225; DF = 5) = 32.080, P < 0.0001; CFI = 0.992; RMSEA = 0.067; SRMR = 0.02). Logistic regression analysis indicated that mpox prevention self-efficacy was significantly associated with mpox-related knowledge (OR 1.107, 95% CI 1.070–1.146), perceived risk awareness (OR 1.338, 95% CI 1.132–1.583), and mpox risk perception (OR 1.154, 95% CI 1.066–1.250). Individuals over 25 years old exhibited lower self-efficacy in mpox prevention (25–34 years: OR = 0.789, 95% CI 0.642–0.970; 35–44 years: OR = 0.572, 95% CI 0.444–0.736; 45 years and older: OR = 0.569, 95% CI 0.394–0.823).

Conclusions:

These findings underscore the importance of targeted interventions aimed at enhancing self-efficacy in mpox prevention by bolstering knowledge, perceived risk awareness, and risk perception. Such initiatives are particularly crucial for middle-aged and older individuals to counteract the age-related decline in self-efficacy. Strengthening self-efficacy through these efforts is essential for fostering sustained preventive behaviors and promoting mental well-being. Ultimately, these interventions can contribute meaningfully to reducing mpox transmission and improving the overall health of the MSM community.


 Citation

Please cite as:

Cai Y, Gao Q, Liu S, Baier M, Xu H, Zhang J, Xu G, Hu F, Wang Y

Mpox Prevention Self-Efficacy and Associated Factors Among Men Who Have Sex With Men in China: Large Cross-Sectional Study

JMIR Public Health Surveill 2025;11:e68400

DOI: 10.2196/68400

PMID: 40020043

PMCID: 11887935

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