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Accepted for/Published in: Online Journal of Public Health Informatics

Date Submitted: Oct 25, 2024
Open Peer Review Period: Dec 18, 2024 - Feb 12, 2025
Date Accepted: Jun 20, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Identifying Substance Use and High-Risk Sexual Behavior Among Sexual and Gender Minority Youth by Using Mobile Phone Data: Development and Validation Study

Beikzadeh M, Holloway IW, Kärkkäinen K, Hong C, Cascalheira C, Wu ES, Boka C, Avandaño A, Sarrafzadeh M

Identifying Substance Use and High-Risk Sexual Behavior Among Sexual and Gender Minority Youth by Using Mobile Phone Data: Development and Validation Study

Online J Public Health Inform 2025;17:e68013

DOI: 10.2196/68013

PMID: 40795338

PMCID: 12360732

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Identifying Substance Use and High-Risk Sexual Behavior Among Sexual and Gender Minority Young People Using Mobile Phone Data: Development and Validation Study

  • Mehrab Beikzadeh; 
  • Ian W. Holloway; 
  • Kimmo Kärkkäinen; 
  • Chenglin Hong; 
  • Cory Cascalheira; 
  • Elizabeth S.C. Wu; 
  • Callisto Boka; 
  • Alexandra Avandaño; 
  • Majid Sarrafzadeh

ABSTRACT

Background:

Sexual and gender minority (SGM) individuals are at heightened risk for substance use and sexually transmitted infections than their non-SGM peers. Collecting mobile phone usage data passively may open new opportunities for personalizing interventions, as behavioral risks could be identified without user input.

Objective:

Our objective was to determine whether passively sensed mobile phone data can be used to identify substance use and sexual risk behaviors for STI and HIV transmission among young SGM who have sex with men.

Methods:

We developed a mobile phone app to collect participants’ messaging, location, and app use data. Based on community-engaged qualitative research, we trained a machine learning model to identify risk behaviors for STI and HIV transmission, such as condomless anal sex, number of sexual partners, and methamphetamine use. We validated these behaviors using self-report and evaluated their association with mobile phone use data.

Results:

We recruited 82 SGM young people who have sex to use our data collection app, and among those users, our model was highly predictive of methamphetamine use and having 6+ sexual partners (F1 scores 0.83 and 0.69 respectively). The model was less predictive of condomless anal sex (F1 score 0.38). Overall, text-based features were found to be most predictive, but app use and location data improved the results, particularly for detecting 6+ sexual partners.

Conclusions:

Our results show that passively collected mobile phone data may be useful in detecting sexual risk behaviors. Expanding data collection may improve the results further, as certain behaviors, such as injection drug use, were quite rare in the study sample. These models may be used to personalize STI and HIV prevention as well as substance use harm reduction interventions.


 Citation

Please cite as:

Beikzadeh M, Holloway IW, Kärkkäinen K, Hong C, Cascalheira C, Wu ES, Boka C, Avandaño A, Sarrafzadeh M

Identifying Substance Use and High-Risk Sexual Behavior Among Sexual and Gender Minority Youth by Using Mobile Phone Data: Development and Validation Study

Online J Public Health Inform 2025;17:e68013

DOI: 10.2196/68013

PMID: 40795338

PMCID: 12360732

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