Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Pediatrics and Parenting

Date Submitted: Oct 24, 2024
Date Accepted: Apr 23, 2025

The final, peer-reviewed published version of this preprint can be found here:

Effects of Cold and Vibration on Venipuncture Pain Management in Children Aged 2-7 Years Old: Randomized Controlled Trial

Hu Ly, Zhou Zy, Wang Ml, Li Sq, Zhou Ls

Effects of Cold and Vibration on Venipuncture Pain Management in Children Aged 2-7 Years Old: Randomized Controlled Trial

JMIR Pediatr Parent 2025;8:e67918

DOI: 10.2196/67918

PMID: 40853779

PMCID: 12377409

External cold or Vibration? Effects of Cold and Vibration on Puncture Pain Management in Children aged 2-7 years old: Randomised Controlled Trial

  • Long-yi Hu; 
  • Zi-yun Zhou; 
  • Ming-li Wang; 
  • Si-qi Li; 
  • Le-shan Zhou

ABSTRACT

Background:

The pain resulting from venipuncture is one of the primary sources of stress during childhood and can have adverse effects on children. Non-pharmacological methods play an important role in alleviating the pain of punctures in children.

Objective:

To investigate the independent and combined effects of cold and vibration in reducing venipuncture pain in children aged two to seven years.

Methods:

A total of 130 children scheduled for venipuncture were randomly assigned to four groups: control, external cold, vibration, and cold combined with vibration. The interventions were applied using a Buzzy® device. and the Face-Legs-Activity-Cry-Consolability Pain Behavior Scale and the Children's Pain Behavior Scale was used to assess pain and resistance behaviors before and during the procedure.

Results:

The external cold, vibration, and cold combined with vibration interventions significantly reduced pain and behavioral changes, with statistically significant differences. The combined intervention group showed the highest compliance and the lowest pain scores.

Conclusions:

External cold and vibration are effective in reducing procedural pain and improving compliance in children aged two to seven years undergoing venipuncture. The combination of cold and vibration yielded the most significant reduction in pain and non-compliance behaviors. Clinical Trial: This study has been registered in the Chinese Clinical Trial Registry registration number: ChiCTR2400079536, 5 January 2024.


 Citation

Please cite as:

Hu Ly, Zhou Zy, Wang Ml, Li Sq, Zhou Ls

Effects of Cold and Vibration on Venipuncture Pain Management in Children Aged 2-7 Years Old: Randomized Controlled Trial

JMIR Pediatr Parent 2025;8:e67918

DOI: 10.2196/67918

PMID: 40853779

PMCID: 12377409

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.