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Accepted for/Published in: JMIR Mental Health

Date Submitted: Oct 4, 2024
Open Peer Review Period: Oct 8, 2024 - Dec 3, 2024
Date Accepted: Nov 28, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Natural Language Processing and Social Determinants of Health in Mental Health Research: AI-Assisted Scoping Review

Scherbakov D, Hubig N, Lenert LA, Alekseyenko AV, Obeid JS

Natural Language Processing and Social Determinants of Health in Mental Health Research: AI-Assisted Scoping Review

JMIR Ment Health 2025;12:e67192

DOI: 10.2196/67192

PMID: 39819656

PMCID: 11756842

Natural Language Processing and Social Determinants of Health in Mental Health Research: An Artificial Intelligence-Assisted Scoping Review

  • Dmitry Scherbakov; 
  • Nina Hubig; 
  • Leslie Andrew Lenert; 
  • Alexander V. Alekseyenko; 
  • Jihad S. Obeid

ABSTRACT

Background:

The usage of natural language processing (NLP) in mental health research is increasing with a wide range of applications and datasets being investigated.

Objective:

This review aims to summarize the usage NLP in mental health research, with a special focus on the types of text datasets and the usage of social determinants of health (SDOH) in NLP projects related to mental health.

Methods:

The search was conducted in September 2024 using a broad search strategy in PubMed, Scopus, and CINAHL Complete. All citations were uploaded to Covidence online software. The screening and extraction process took place in Covidence with the help of a custom large language model (LLM) module developed by our team. This LLM module was calibrated and tuned to substitute human reviewers.

Results:

The screening process, assisted by the custom LLM, led to the inclusion of 1,768 studies in the final review. The majority of the reviewed studies (n=665, 42.8%) utilized clinical data as their primary text dataset, followed by social media datasets (n=523, 33.7%). The United States contributed the highest number of studies (n=568, 36.6%), with depression (n=438, 28.2%) and suicide (n=240, 15.5%) being the most frequently investigated mental health issues. Traditional demographic variables such as age (n=877, 56.5%) and gender (n=760, 49.0%) were commonly extracted, while SDOH factors were less frequently reported, with urban/rural status being the most used (n=19, 1.2%). Over half of the citations (n=826, 53.2%) did not provide clear information on dataset accessibility, although a sizable number of studies (n=304, 19.6%) made their datasets publicly available.

Conclusions:

This scoping review underscores the significant role of clinical notes and social media in NLP-based mental health research. Despite the clear relevance of SDOH to mental health, their underutilization presents a gap in current research. This review can be a starting point for researchers looking for an overview of mental health projects using text data. Discovered datasets could be used to place more emphasis on SDOH in future studies.


 Citation

Please cite as:

Scherbakov D, Hubig N, Lenert LA, Alekseyenko AV, Obeid JS

Natural Language Processing and Social Determinants of Health in Mental Health Research: AI-Assisted Scoping Review

JMIR Ment Health 2025;12:e67192

DOI: 10.2196/67192

PMID: 39819656

PMCID: 11756842

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