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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Sep 10, 2024
Date Accepted: Apr 25, 2025

The final, peer-reviewed published version of this preprint can be found here:

“PrevenganT2,” a Culturally Responsive Family-Based Diabetes Prevention Intervention for Hispanic or Latino Adults at High Risk for Type 2 Diabetes: Protocol for a Proof-of-Concept Evaluation

Franklin BE, Meulenberg BL, Beaulieu EZ, Cisneros-Macias J, Cao Y, Carbajal-Salisbury S, Villalta J, Flores N, Fuentes V, Hernandez MC, Parry-Alba D, Rodriguez C, Rodriguez Y, Zavala Orozco VS, Asnaani A, Sanchez-Birkhead A, Baucom KJ

“PrevenganT2,” a Culturally Responsive Family-Based Diabetes Prevention Intervention for Hispanic or Latino Adults at High Risk for Type 2 Diabetes: Protocol for a Proof-of-Concept Evaluation

JMIR Res Protoc 2025;14:e66317

DOI: 10.2196/66317

PMID: 40811792

PMCID: 12395107

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

"PrevenganT2," Culturally-Responsive Family-Based Diabetes Prevention Intervention for Hispanic/Latino Adults at High Risk for Type 2 Diabetes: Protocol for a Proof-of-Concept Evaluation

  • Brooke E. Franklin; 
  • Brynn L. Meulenberg; 
  • Elizabeth Z. Beaulieu; 
  • Jessica Cisneros-Macias; 
  • Yiqing Cao; 
  • Sara Carbajal-Salisbury; 
  • Jeannette Villalta; 
  • Nelamaria Flores; 
  • Virginia Fuentes; 
  • Maria C. Hernandez; 
  • Diana Parry-Alba; 
  • Carmen Rodriguez; 
  • Yolanda Rodriguez; 
  • Veronica S. Zavala Orozco; 
  • Anu Asnaani; 
  • Ana Sanchez-Birkhead; 
  • Katherine J.W. Baucom

ABSTRACT

Background:

Despite the efficacy of lifestyle interventions for delaying diabetes, community translations to date have failed to engage Hispanic/Latino participants effectively. Previously identified barriers to engagement include lack of family support and the burden of time-intensive year-long programs. Integrating family members and reducing program length may have the potential to increase engagement in lifestyle interventions to prevent type 2 diabetes in Hispanic/Latino individuals.

Objective:

Given the potential impact of cultural adaptation on such interventions, our community-academic research team used the Obesity Research Behavioral Intervention Trials (ORBIT) model to guide an adaptation of the core 16 modules of the National DPP’s PrevengaT2 curriculum to meet the needs of Hispanic/Latino communities in Utah. We describe our evaluation of this adaptation in an ongoing proof-of-concept trial. We evaluate whether Hispanic/Latino participants at high risk for type 2 diabetes increase their weekly moderate-to-vigorous physical activity (MVPA) in the context of an ongoing proof-of-concept trial of the adaptation.

Methods:

Target participants at risk for type 2 diabetes and a family member will complete PrevenganT2. In earlier phases of a larger project, our academic-community research team created the 14-week lifestyle intervention by adapting the Centers for Disease Control and Prevention’s PrevengaT2 curriculum. Objective MVPA will be measured for 7 days at pre- and post-intervention using ActiGraph GT3X-BT accelerometers. Participants will additionally complete questionnaires at pre- and post-intervention, and weight and self-reported MVPA will be recorded regularly at lifestyle intervention classes. Physical activity data will be analyzed to determine the percent of target participants with clinically significant pre-post increases in MVPA.

Results:

Data collection is in progress and is planned to conclude in October 2024. We expect that results will be available for publication by June 2024.

Conclusions:

This study will provide essential insights into the efficacy of a novel, culturally adapted type 2 diabetes intervention in Hispanic/Latino adults. Findings will inform future research directions for lifestyle interventions to prevent type 2 diabetes in Hispanic/Latino adults.


 Citation

Please cite as:

Franklin BE, Meulenberg BL, Beaulieu EZ, Cisneros-Macias J, Cao Y, Carbajal-Salisbury S, Villalta J, Flores N, Fuentes V, Hernandez MC, Parry-Alba D, Rodriguez C, Rodriguez Y, Zavala Orozco VS, Asnaani A, Sanchez-Birkhead A, Baucom KJ

“PrevenganT2,” a Culturally Responsive Family-Based Diabetes Prevention Intervention for Hispanic or Latino Adults at High Risk for Type 2 Diabetes: Protocol for a Proof-of-Concept Evaluation

JMIR Res Protoc 2025;14:e66317

DOI: 10.2196/66317

PMID: 40811792

PMCID: 12395107

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