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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Aug 13, 2024
Date Accepted: May 13, 2025

The final, peer-reviewed published version of this preprint can be found here:

Assessing Clinical Impressions of Early Warning Score Integration With the Rapid Response Team: Protocol for a Prospective Cohort Study

Tran A, Ramchandani R, Brehaut J, Hudek N, Haines J, Watpool I, Porteous R, Kyeremanteng K, Hartwick M, Thavorn K, Hooper J, Kubelik D, Herry C, Scales N, Hryciw B, Abou-Khalil J, Perry J, Bredeson C, Seely A

Assessing Clinical Impressions of Early Warning Score Integration With the Rapid Response Team: Protocol for a Prospective Cohort Study

JMIR Res Protoc 2025;14:e65360

DOI: 10.2196/65360

PMID: 40742731

PMCID: 12355135

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Assessing Clinical Impressions of Early Warning Score Integration with the Rapid Response Team: Protocol for a Prospective Cohort Study

  • Alexandre Tran; 
  • Rashi Ramchandani; 
  • Jamie Brehaut; 
  • Natasha Hudek; 
  • Jessica Haines; 
  • Irene Watpool; 
  • Rebecca Porteous; 
  • Kwadwo Kyeremanteng; 
  • Michael Hartwick; 
  • Kednapa Thavorn; 
  • Jonathan Hooper; 
  • Dalibor Kubelik; 
  • Christophe Herry; 
  • Nathan Scales; 
  • Brett Hryciw; 
  • Jad Abou-Khalil; 
  • Jeffrey Perry; 
  • Christopher Bredeson; 
  • Andrew Seely

ABSTRACT

Background:

Growing evidence has suggested the use of Early Warning Scores (EWSs) which integrate real-time vital sign monitoring, can help Rapid Response Teams (RRTs) proactively identify patients at risk of deterioration. The Visensia Safety Index (VSI) is a novel EWS based on continuous vital sign monitoring.

Objective:

This study aims to evaluate the trial implementation of a portable continuous vital sign monitoring system paired with a novel machine learning based index to predict potential clinical deterioration.

Methods:

This two-phase, prospective cohort study will be conducted at the Ottawa Hospital. Eligible patients will be monitored using the VSI with alerts to trigger rapid response team evaluation. Subsequently, we will conduct 30–45-minute semi-structured interviews of consenting healthcare providers to explore the clinical impressions of the trial implementation.

Results:

As of August 2024 when the protocol manuscript was submitted, we have enrolled 25 patients.

Conclusions:

The execution of this interventional study requires a multidisciplinary effort. The study employs continuous vital sign monitoring, combined with prediction of deterioration risk, utilized to activate the RRT. Evaluating feasibility and clinical impressions of this trial implementation is the first step of exploring monitoring based predictive decision support.


 Citation

Please cite as:

Tran A, Ramchandani R, Brehaut J, Hudek N, Haines J, Watpool I, Porteous R, Kyeremanteng K, Hartwick M, Thavorn K, Hooper J, Kubelik D, Herry C, Scales N, Hryciw B, Abou-Khalil J, Perry J, Bredeson C, Seely A

Assessing Clinical Impressions of Early Warning Score Integration With the Rapid Response Team: Protocol for a Prospective Cohort Study

JMIR Res Protoc 2025;14:e65360

DOI: 10.2196/65360

PMID: 40742731

PMCID: 12355135

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