Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Jul 26, 2024
Date Accepted: Aug 21, 2025

The final, peer-reviewed published version of this preprint can be found here:

Acceptability, Needs, Concerns, and Barriers to Digital-Based Interventions for the Prevention of Mother-to-Child Transmission of HIV: Systematic Review and Qualitative Meta-Aggregation

Maulana S, Ibrahim K, Arbing RH, Pramukti I, Nugrahani AD, Armini LN, Iqhrammullah M, Chen WT

Acceptability, Needs, Concerns, and Barriers to Digital-Based Interventions for the Prevention of Mother-to-Child Transmission of HIV: Systematic Review and Qualitative Meta-Aggregation

JMIR Med Inform 2025;13:e64816

DOI: 10.2196/64816

PMID: 41116701

PMCID: 12538026

Acceptability, Needs, Concerns, and Barriers to Digital-Based Interventions for the Prevention of Mother-to-Child Transmission of HIV: A Systematic Review and Qualitative Meta-aggregation

  • Sidik Maulana; 
  • Kusman Ibrahim; 
  • Rachel H.A. Arbing; 
  • Iqbal Pramukti; 
  • Annisa Dewi Nugrahani; 
  • Luh Nik Armini; 
  • Muhammad Iqhrammullah; 
  • Wei-Ti Chen

ABSTRACT

Background:

Telehealth interventions have the potential to support preventing mother-to-child HIV transmission (PMTCT) initiatives. Nevertheless, there is a lack of reviews to explore patient experiences and attitudes toward digital technology interventions.

Objective:

The study aims of the study was to explore patient experiences and attitudes toward digital health technology interventions in promoting PMTCT.

Methods:

The study used a systematic review and qualitative meta-aggregation adhered to the preferred reporting items for systematic review and meta-analysis (PRISMA) and Joanna Briggs Institute (JBI) Reviewer’s Manual. Electronic databases such as Scopus, PubMed, CINAHL, and Wiley were comprehensively searched. Eligibility criteria of this study are qualitative study focused on mothers living with HIV and their healthcare providers, exploring their experiences and attitudes toward digital health interventions for the PMTCT of HIV. We assessed the quality of the studies using the JBI Critical Appraisal tools for qualitative research and the Mixed Methods Appraisal Tool (MMAT) for mixed methods studies. The study used meta-aggregation to synthesis of included qualitative studies.

Results:

The search yielded Eight included studies were analyzed. The study revealed four synthesized finding which included (1) positive acceptability of using health intervention for PMTCT, (2) patients' need education, (3) concerns about confidentiality, (4) personal, interpersonal, and healthcare barriers to adhering to care. Nine categories include good perceived-satisfaction, enhanced adherence, patient needs education, support systems, reminders, concerns about confidentiality, lack of family support, financial, and bad attitudes of provider.

Conclusions:

The study demonstrates that digital health interventions are well-received by HIV-positive pregnant women, but attention to confidentiality, family support, financial barriers, and provider attitudes is essential. These findings suggest that nurses and other healthcare professional can utilize mobile health interventions to enhance PMTCT outcomes through continuous education, support, and by addressing barriers to care.


 Citation

Please cite as:

Maulana S, Ibrahim K, Arbing RH, Pramukti I, Nugrahani AD, Armini LN, Iqhrammullah M, Chen WT

Acceptability, Needs, Concerns, and Barriers to Digital-Based Interventions for the Prevention of Mother-to-Child Transmission of HIV: Systematic Review and Qualitative Meta-Aggregation

JMIR Med Inform 2025;13:e64816

DOI: 10.2196/64816

PMID: 41116701

PMCID: 12538026

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.