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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Aug 21, 2024
Date Accepted: Nov 25, 2024

The final, peer-reviewed published version of this preprint can be found here:

Internet-Based Dementia Prevention Intervention (DementiaRisk): Protocol for a Randomized Controlled Trial and Knowledge Translation

Levinson AJ, Ayers S, Clark S, Woodburn R, Dobbins M, Duarte D, Grad R, Kates N, Marr S, Oliver D, Papaioannou A, Saperson K, Siu H, Strudwick G, Sztramko R, Neil-Sztramko S

Internet-Based Dementia Prevention Intervention (DementiaRisk): Protocol for a Randomized Controlled Trial and Knowledge Translation

JMIR Res Protoc 2025;14:e64718

DOI: 10.2196/64718

PMID: 39869903

PMCID: 11811655

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Dementia Prevention Internet-Based Intervention: Protocol for a Randomized Controlled Trial and Knowledge Translation

  • Anthony J. Levinson; 
  • Stephanie Ayers; 
  • Sandra Clark; 
  • Rebekah Woodburn; 
  • Maureen Dobbins; 
  • Dante Duarte; 
  • Roland Grad; 
  • Nick Kates; 
  • Sharon Marr; 
  • Doug Oliver; 
  • Alexandra Papaioannou; 
  • Karen Saperson; 
  • Henry Siu; 
  • Gillian Strudwick; 
  • Richard Sztramko; 
  • Sarah Neil-Sztramko

ABSTRACT

Background:

Research has shown that engaging in a range of healthy lifestyle or behavioural factors can help reduce the risk of developing dementia. Improved knowledge of modifiable risk factors for dementia may help to engage people to reduce their risk, with beneficial impacts on individual and public health. Moreover, many guidelines emphasize the importance of providing education and online resources for dementia prevention. Internet-based interventions may be effective, but few have been studied rigorously or widely disseminated. We created DementiaRisk.ca, an award-winning web- and email-based education platform for the public focused on modifiable risk factors, featuring multimedia e-learning and email ‘micro-learning’ content, to help raise awareness and improve knowledge of actions to reduce dementia risk.

Objective:

This protocol describes a randomized controlled trial to evaluate whether exposure to DementiaRisk changes knowledge of dementia risk factors, intention to engage in risk reduction activities, and health behaviours related to dementia risk reduction; and to explore qualitative aspects such as participants’ engagement and satisfaction with the intervention, as well as barriers and facilitators to use.

Methods:

Using a sequential explanatory mixed methods design, this study first conducts a quantitative analysis followed by a qualitative inquiry to evaluate outcomes and feasibility. Participants are randomly assigned to 2 groups: one accessing DementiaRisk and the other receiving alterative e-learning on Mild Cognitive Impairment. Assessments will be delivered at the following timepoints: baseline (T1), at 4-weeks (T2), and at 2-months post-intervention (T3).

Results:

This study was approved by the Hamilton Integrated Research Ethics Board on August 24, 2022 (project ID 14886) and received funding in February 2023. Recruitment took place from March 28th, 2023 – April 28th, 2023, with the final participants completing the intervention by August 18th, 2023. Analyses and interpretation of data is ongoing.

Conclusions:

DementiaRisk is a readily scalable technology-enhanced solution for dementia prevention education. It has been designed using evidence-based principles of multimedia learning. It has the potential to scale and spread widely using the open internet, so may be able to reach a wider audience than traditional in-person educational interventions. Clinical Trial: ClinicalTrials.gov NCT05383118; May 18, 2022.


 Citation

Please cite as:

Levinson AJ, Ayers S, Clark S, Woodburn R, Dobbins M, Duarte D, Grad R, Kates N, Marr S, Oliver D, Papaioannou A, Saperson K, Siu H, Strudwick G, Sztramko R, Neil-Sztramko S

Internet-Based Dementia Prevention Intervention (DementiaRisk): Protocol for a Randomized Controlled Trial and Knowledge Translation

JMIR Res Protoc 2025;14:e64718

DOI: 10.2196/64718

PMID: 39869903

PMCID: 11811655

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