Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jul 3, 2024
Date Accepted: Mar 17, 2025

The final, peer-reviewed published version of this preprint can be found here:

Correlation Between Prakriti (Body Constitution) and Severity of Structural Alterations in the Lungs of Patients With SARS-CoV-2: Protocol for a Retrospective Cross-Sectional Study

Gudadhe R, Sawarkar G, Deshpande A

Correlation Between Prakriti (Body Constitution) and Severity of Structural Alterations in the Lungs of Patients With SARS-CoV-2: Protocol for a Retrospective Cross-Sectional Study

JMIR Res Protoc 2026;15:e63916

DOI: 10.2196/63916

PMID: 41505696

PMCID: 12782462

Correlation Between Prakriti (Body Constitution) and Severity of Structural Alterations in the Lungs of Patients With SARS-CoV-2: Protocol for a Retrospective Cross-Sectional Study

  • Rugaved Gudadhe; 
  • Gaurav Sawarkar; 
  • Amol Deshpande

Background:

SARS CoV-2, a novel coronavirus, initially appeared in the Wuhan, China, in the end of 2019 and had infected above 31 million people worldwide. Infection can range from asymptomatic to multi-organ failure requiring prompt treatment. 80% of SARS-CoV-2 patients experienced mild to moderate illness, while 5% developed serious illness. Physicians can evaluate a patient's digestive system (Koshtha), digestive capacity (Agni), strength (Bala), and longevity (Ayu) using the bodily Constitution (Deha Prakriti). It also helps doctors estimate a patient's illness risk, severity, disease activity scores, and hematological, pathological, and biochemical changes. The study investigated the association between bodily composition (Deha Prakriti) and severity, as shown by structural lung abnormalities in SARS-CoV-2 patients.

Objective:

To study the correlation between severity of Prakriti and structural alterations in the lungs of SARS-COV-2 patients.

Methods:

This is a retrospective cross-sectional study of SARS-CoV-2 patients. The research data will be collected from September 1st, 2020 through May 11th, 2021 as India suffering through the second wave of pandemic during this period. It is the retrospective collection of data from hospital records, the data will come from the Acharya Vinoba Bhave Rural Hospital in Sawangi (Meghe), Wardha, Maharashtra, India. Patients will be contacted via telephone and encouraged to visit the OPD and IPD at these institutions or in rural and urban areas of Wardha city. A structured case proforma and a Prakriti assessment questionnaire will be used to evaluate lung structural changes during the COVID-19-positive period.

Results:

Results will be recorded from the observations of subjective and objective parameters. The study's primary outcome is to establish a relationship between abnormalities in the structure of the lungs in COVID patients and body constitution. The study's secondary outcome will provide a better understanding of the body constitution that is most susceptible to structural changes and severity in COVID-19 patients, as well as information about preventive medicine.

Conclusions:

Statistical investigation will lead to the conclusion that there is a specific association between structural abnormalities in COVID patients' lungs and their body constitution. Prakriti was identified as being more prone to structural changes and severity in COVID-19 patients and offering insights into preventive therapy.

International Registered Report:

PRR1-10.2196/63916


 Citation

Please cite as:

Gudadhe R, Sawarkar G, Deshpande A

Correlation Between Prakriti (Body Constitution) and Severity of Structural Alterations in the Lungs of Patients With SARS-CoV-2: Protocol for a Retrospective Cross-Sectional Study

JMIR Res Protoc 2026;15:e63916

DOI: 10.2196/63916

PMID: 41505696

PMCID: 12782462

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.