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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jun 29, 2024
Date Accepted: Mar 12, 2025

The final, peer-reviewed published version of this preprint can be found here:

Enhancing Physician-Patient Communication in Oncology Using GPT-4 Through Simplified Radiology Reports: Multicenter Quantitative Study

Yang X, Xiao Y, Liu D, Shi H, Deng H, Huang J, Zhang Y, Liu D, Liang M, Jin X, Sun Y, Yao J, Zhou X, Guo W, He Y, Tang W, Xu C

Enhancing Physician-Patient Communication in Oncology Using GPT-4 Through Simplified Radiology Reports: Multicenter Quantitative Study

J Med Internet Res 2025;27:e63786

DOI: 10.2196/63786

PMID: 40245397

PMCID: 12046253

Enhancing Doctor-Patient Communication in Oncology through Simplified Radiology Reports: A Multicenter Quantitative Study Using GPT-4

  • Xiongwen Yang; 
  • Yi Xiao; 
  • Di Liu; 
  • Huiyou Shi; 
  • Huiyin Deng; 
  • Jian Huang; 
  • Yun Zhang; 
  • Dan Liu; 
  • Maoli Liang; 
  • Xing Jin; 
  • Yongpan Sun; 
  • Jing Yao; 
  • XiaoJiang Zhou; 
  • Wankai Guo; 
  • Yang He; 
  • Weijuan Tang; 
  • Chuan Xu

ABSTRACT

Background:

Effective doctor-patient communication is essential in clinical practice, especially in oncology, where radiology reports play a crucial role. These reports are often filled with technical jargon, making them challenging for patients to understand and affecting their engagement and decision-making. Large Language Models (LLMs), such as Generative Pretrained Transformer-4 (GPT-4), offer a novel approach to simplifying these reports and potentially enhancing communication and patient outcomes.

Objective:

To assess the feasibility and effectiveness of using GPT-4 to simplify oncological radiology reports to improve doctor-patient communication.

Methods:

In a retrospective study approved by the Ethics Review Committees of multiple hospitals, 698 radiology reports of malignant tumors from October to December 2023 were analyzed. Seventy reports were selected to develop templates and scoring scales for GPT-4 to create simplified interpretative radiology reports (IRRs). Radiologists checked the consistency between original radiology reports (ORRs) and IRRs, while middle-aged volunteers with high school education and no medical background assessed readability. Doctors evaluated communication efficiency through simulated consultations.

Results:

Transforming ORRs into IRRs resulted in clearer reports, with word count increasing from 818.74 to 1025.82 (P<0.001), volunteers' reading time decreasing from 672.24 seconds to 590.39 seconds (P<0.001), and reading rate increasing from 72.44 words/min to 104.62 words/min (P<0.001). Doctor-patient communication time significantly reduced from 1117.30 seconds to 746.84 seconds (P<0.001), and patient comprehension scores improved from 5.49 to 7.82 (P<0.001).

Conclusions:

This study demonstrates the significant potential of LLMs, specifically GPT-4, to facilitate medical communication by simplifying oncological radiology reports. Simplified reports enhance patient understanding and the efficiency of doctor-patient interactions, suggesting a valuable application of AI in clinical practice to improve patient outcomes and healthcare communication. Clinical Trial: No application.


 Citation

Please cite as:

Yang X, Xiao Y, Liu D, Shi H, Deng H, Huang J, Zhang Y, Liu D, Liang M, Jin X, Sun Y, Yao J, Zhou X, Guo W, He Y, Tang W, Xu C

Enhancing Physician-Patient Communication in Oncology Using GPT-4 Through Simplified Radiology Reports: Multicenter Quantitative Study

J Med Internet Res 2025;27:e63786

DOI: 10.2196/63786

PMID: 40245397

PMCID: 12046253

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