Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.
Who will be affected?
Readers: No access to all 28 journals. We recommend accessing our articles via PubMed Central
Authors: No access to the submission form or your user account.
Reviewers: No access to your user account. Please download manuscripts you are reviewing for offline reading before Wednesday, July 01, 2020 at 7:00 PM.
Editors: No access to your user account to assign reviewers or make decisions.
Copyeditors: No access to user account. Please download manuscripts you are copyediting before Wednesday, July 01, 2020 at 7:00 PM.
Ramirez M, Gebauer M, Mermier C, Little J, Lin L, Palley G, Hsiao YY, Mota Alvidrez R, Mang ZA, Amorim FT, Tricoli V, De Castro Magalhães F
The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial
The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: a Protocol for a Randomized-controlled, crossover, Clinical Trial
Marissa Ramirez;
Maja Gebauer;
Christine Mermier;
Jonathan Little;
Luotao Lin;
Gabriel Palley;
Yu Yu Hsiao;
Roberto Mota Alvidrez;
Zach A Mang;
Fabiano Trigueiro Amorim;
Valmor Tricoli;
Flavio De Castro Magalhães
ABSTRACT
Background:
Type 2 diabetes (T2D) is preceded by prediabetes that places a great burden on patients and society. These conditions are significantly associated with poor glycemic control that is improved by resistance exercise. It has been suggested that resistance exercise should be performed with a high degree of effort for improving glucose metabolism, but this is associated with negative psychological responses that might lead to lower long-term adherence.
Objective:
To investigate the effect of the degree of effort during a resistance exercise session on glycemic control and psychological responses in individuals living with prediabetes or T2D.
Methods:
Fifteen participants will perform 3 randomized experimental conditions, lasting ~48-h each, separated by at least 4 washout days. In 2 of these, resistance exercise will be performed that will differ in the degree of effort in each set (high vs low), but equalized in total weight lifted and session duration. Participants will also complete a sedentary (control) condition. After each session, psychological responses will be assessed (exertion, affect, enjoyment, self-efficacy, and discomfort). Glycemic control will be assessed by a continuous glucose monitoring device throughout the ~48-h of each experimental situation. Food and drink will be provided to participants and physical activity levels will be assessed by accelerometry.
Results:
This study has been funded, and data collection is expected to take place between July 2024 and May 2025. Final manuscript submission should happen by August 2025.
Conclusions:
The results of this project might encourage individuals living with prediabetes and T2D to engage in resistance exercise while better informing exercise specialists on how to best incorporate resistance exercise in their client’s or patient’s routine. Clinical Trial: Clinical trial registry number: https://clinicaltrials.gov/study/NCT06208189
Citation
Please cite as:
Ramirez M, Gebauer M, Mermier C, Little J, Lin L, Palley G, Hsiao YY, Mota Alvidrez R, Mang ZA, Amorim FT, Tricoli V, De Castro Magalhães F
The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial