Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Apr 18, 2024
Date Accepted: Nov 21, 2024

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial

López-del-Hoyo Y, Fernández-Martínez S, Perez-Aranda A, Monreal-Bartolomé A, Bareló-Soler A, Camarero-Grados L, Armas-Landaeta C, Guzmán-Parra J, Carbonell V, Campos D, Chen X, García-Campayo J

Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial

J Med Internet Res 2025;27:e59653

DOI: 10.2196/59653

PMID: 39899345

PMCID: 11833273

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Effectiveness of an online self-guided intervention (MINDxYOU) for reducing stress and promoting mental health among health professionals: results from a stepped wedge cluster-randomized trial

  • Yolanda López-del-Hoyo; 
  • Selene Fernández-Martínez; 
  • Adrian Perez-Aranda; 
  • Alicia Monreal-Bartolomé; 
  • Alberto Bareló-Soler; 
  • Loreto Camarero-Grados; 
  • Carilene Armas-Landaeta; 
  • José Guzmán-Parra; 
  • Vera Carbonell; 
  • Daniel Campos; 
  • Xinyuan Chen; 
  • Javier García-Campayo

ABSTRACT

Background:

The high levels of sustained stress that health professionals often experience pose a significant risk factor for developing mental health problems such as anxiety, depression, and somatic symptoms that not only affect their wellbeing but also have major social and organizational consequences. Different interventions, including those based on “third wave” psychotherapy principles (i.e., mindfulness, compassion, acceptance), have proved to be effective for reducing stress in this population. Among them, those delivered online constitute a promising alternative with notable advantages in terms of accessibility and flexibility, yet some adherence inconveniences that may limit their efficacy.

Objective:

The objective of this study was to evaluate the effectiveness of the MINDxYOU program, an online self-guided intervention based on “third wave” psychotherapy principles, to reduce perceived stress and promote mental health in a sample of health professionals.

Methods:

Following a stepped wedge cluster-randomized design, 357 health professionals working for different health centers in two Spanish regions (Aragón and Málaga) were recruited and distributed into 6 clusters, which were randomly allocated to three possible sequences. Sequentially, they were given access to the MINDxYOU program. This self-guided web-based program, which was designed to be completed in 8 consecutive weeks, included weekly contact (text message, phone call, or email) with the research team meant to foster adherence to the program. The study participants were assessed 5 times, once every 8 weeks. Every assessment was conducted online, and perceived stress was the primary outcome of the study; other clinical aspects (i.e., anxiety, depression, and somatization) and process variables (i.e., resilience, mindfulness, compassion, and acceptance) were also evaluated.

Results:

The online program was initiated by 229 participants, 112 (48.9%) of whom were completers (i.e., completed at least 3 of the 4 modules). Perceived stress demonstrated a significant reduction both when considering the entire sample (B= -1.08, SE= 0.51, P= .034) and the sample of completers (B= -1.84, SE= 0.62, P= .003). Intra-cluster analysis revealed that pre- vs. post-intervention moderate effects were present in two clusters, and that these were maintained in subsequent assessments. The linear mixed-effects models also showed that most secondary outcomes and process variables experienced significant effects when comparing the intervention and control phases.

Conclusions:

The MINDxYOU program was effective in reducing perceived stress and promoting mental health, as well as increasing certain aspects, such as resilience, mindfulness facets, and self-compassion. Adherence to the intervention was moderate, while program utilization was notable compared to similar interventions. Clinical Trial: This study was registered on ClinicalTrials.gov on 29/06/2022; registration number: NCT05436717.


 Citation

Please cite as:

López-del-Hoyo Y, Fernández-Martínez S, Perez-Aranda A, Monreal-Bartolomé A, Bareló-Soler A, Camarero-Grados L, Armas-Landaeta C, Guzmán-Parra J, Carbonell V, Campos D, Chen X, García-Campayo J

Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial

J Med Internet Res 2025;27:e59653

DOI: 10.2196/59653

PMID: 39899345

PMCID: 11833273

The author of this paper has made a PDF available, but requires the user to login, or create an account.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.