Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Mar 27, 2024
Date Accepted: Nov 12, 2024

The final, peer-reviewed published version of this preprint can be found here:

Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study

Jiang X, Wang B

Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study

JMIR Med Inform 2024;12:e58812

DOI: 10.2196/58812

PMID: 39740105

PMCID: 11706445

Enhancing Clinical Decision-Making: Predicting Readmission Risk in Heart Failure Patients with Machine Learning

  • Xiangkui Jiang; 
  • Bingquan Wang

ABSTRACT

Background:

Heart failure sufferers frequently face the likelihood of rehospitalization following an initial stay. Although several risk assessment tools have been developed to aid in clinical decision-making, clinicians and patients' families continue to encounter significant challenges in determining shared decision-making regarding maintenance versus hospice transition. To address these challenges, it is crucial to devise more precise predictive tools, which can assist medical professionals and relatives in the care management of individuals with heart failure. Currently, effective predictive models for the Chinese heart failure patient population are still insufficient, which limits our ability to accurately assess patient prognosis and implement personalized treatment strategies.

Objective:

The present study has formulated a predictive model for assessing the likelihood of readmission among patients diagnosed with heart failure.

Methods:

In this study, we analyzed data from 1,948 heart failure patients in a hospital in Sichuan Province between 2016 and 2019. By applying three variable selection strategies, 29 relevant variables were identified. Subsequently, we constructed six predictive models using different algorithms: logistic regression (LR), support vector machine (SVM), gradient boosting machine (GBM), extreme gradient boosting (XGBoost), multilayer perceptron (MLP), and graph convolutional network (GCN).

Results:

The graph convolutional network model showed the highest prediction accuracy with an area under the curve (AUC) of 0.866, accuracy of 77.6%, sensitivity of 58.54%, and specificity of 90.42%.

Conclusions:

The model crafted in this study proves its effectiveness in forecasting the likelihood of readmission among heart failure patients, thus serving as a crucial reference for clinical decision-making.


 Citation

Please cite as:

Jiang X, Wang B

Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study

JMIR Med Inform 2024;12:e58812

DOI: 10.2196/58812

PMID: 39740105

PMCID: 11706445

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.