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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Mar 21, 2024
Date Accepted: Mar 8, 2025

The final, peer-reviewed published version of this preprint can be found here:

Psychological Factors Influencing Appropriate Reliance on AI-enabled Clinical Decision Support Systems: Experimental Web-Based Study Among Dermatologists

Küper A, Lodde G, Livingstone E, Schadendorf D, Krämer N

Psychological Factors Influencing Appropriate Reliance on AI-enabled Clinical Decision Support Systems: Experimental Web-Based Study Among Dermatologists

J Med Internet Res 2025;27:e58660

DOI: 10.2196/58660

PMID: 40184614

PMCID: 12008695

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Psychological Traits Influencing Appropriate Reliance on AI-enabled Clinical Decision Support Systems: an Experimental Study

  • Alisa Küper; 
  • Georg Lodde; 
  • Elisabeth Livingstone; 
  • Dirk Schadendorf; 
  • Nicole Krämer

ABSTRACT

Background:

AI-enabled decision support systems are crucial tools in medical practice; however, their reliability is not absolute, necessitating human oversight for final decision-making. Human reliance on such systems can vary, influenced by factors like individual psychological traits and levels of experience among physicians.

Objective:

This study aimed to explore the psychological traits impacting subjective trust and reliance on medical AI advice, specifically examining relative AI reliance and relative self-reliance to assess appropriateness of reliance.

Methods:

A survey involving 223 dermatologists included lesion image classification tasks and validated questionnaires assessing subjective trust, propensity to trust technology, affinity for technology interaction, control beliefs, need for cognition, along with inquiries into medical experience and decision confidence.

Results:

Participants' accuracy significantly improved with AI support (t222=-3.3; P<.001; Cohen d=4.5) but showing only a 1% average increase. Reliance on AI was stronger with correct advice than incorrect advice (t222=4.2; P<.001; Cohen d=0.1). Notably, participants demonstrated a mean relative AI reliance of 10.0% (139/1384) and relative self-reliance of 85.1% (487/569), indicating a high level of self-reliance but only a low amount of AI reliance. Propensity to trust technology influenced AI reliance, mediated by trust (indirect effect = .024; 95% CI 0.0-0.0; P<.001), and medical experience negatively predicted AI reliance (indirect effect = -.001; 95% CI -0.0 to -0.0; P<.001).

Conclusions:

Findings underscore the need to design AI support systems in a way that assists less experienced users with a high propensity to trust technology to identify potential AI errors, while encouraging experienced physicians to actively engage with system recommendations and potentially reassess initial decisions.


 Citation

Please cite as:

Küper A, Lodde G, Livingstone E, Schadendorf D, Krämer N

Psychological Factors Influencing Appropriate Reliance on AI-enabled Clinical Decision Support Systems: Experimental Web-Based Study Among Dermatologists

J Med Internet Res 2025;27:e58660

DOI: 10.2196/58660

PMID: 40184614

PMCID: 12008695

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