Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Mar 18, 2024
Date Accepted: Apr 14, 2025

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of Telemedicine on Wound-Related and Patient-Reported Outcomes in Patients With Chronic Wounds: Systematic Review and Meta-Analysis

Zhang X, Guo Z, Duan Y, Sun C, Luo J

Effectiveness of Telemedicine on Wound-Related and Patient-Reported Outcomes in Patients With Chronic Wounds: Systematic Review and Meta-Analysis

JMIR Mhealth Uhealth 2025;13:e58553

DOI: 10.2196/58553

PMID: 40493508

PMCID: 12173094

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Effect of telemedicine on wound-related and patient-reported outcomes in chronic wound patients: A systematic review and meta-analysis

  • Xiaoyan Zhang; 
  • Zhanghui Guo; 
  • Yu Duan; 
  • Chao Sun; 
  • Jiayin Luo

ABSTRACT

Background:

Telemedicine (TM) may bring new vitality and opportunities to the field of wound care and has been advocated as a potential and feasible strategy for chronic wound management.

Objective:

This systematic review and meta-analysis aimed to assess the effectiveness of TM on wound-related outcomes and patient-reported outcomes (PROs) in patients with chronic wounds.

Methods:

A comprehensive search of nine databases—PubMed, Embase, PsycINFO, Cochrane Library, CINAHL, Web of Science, China National Knowledge Infrastructure database, Wanfang Database, and VIP Database—was performed to identify eligible randomized controlled trials (RCTs) that investigated the effectiveness of TM for patients with chronic wounds. Two reviewers independently conducted the study selection, data extraction, risk of bias assessment, and evaluation of evidence quality. Meta-analyses were performed where feasible; otherwise, narrative summaries were provided.

Results:

A total of 22 RCTs involving 2370 participants met the inclusion criteria. Overall, the utilization of TM significantly improved the healing rate, healing score, healing time, amputation rate, pain, and quality of life of chronic wound patients. However, no significant differences in mortality, depression, anxiety, or patient satisfaction were observed. Furthermore, the subgroup analyses revealed significant effects in TM of short-term, for pressure injuries and venous ulcers, as well as TM in conjunction with a face-to-face component on improvements to the healing rate. The subgroup analyses showed a significant decrease in healing time with TM for venous ulcers or in conjunction with a face-to-face component. The subgroup analyses also indicated significant effects of TM with ≥ 2 types, for diabetes foot ulcers, in conjunction with a face-to-face component, or in combination with communication components in improving the amputation rate. Therefore, TM appears to be an effective method for chronic wound management.

Conclusions:

A total of 22 RCTs involving 2370 participants met the inclusion criteria. Overall, the utilization of TM significantly improved the healing rate, healing score, healing time, amputation rate, pain, and quality of life of chronic wound patients. However, no significant differences in mortality, depression, anxiety, or patient satisfaction were observed. Furthermore, the subgroup analyses revealed significant effects in TM of short-term, for pressure injuries and venous ulcers, as well as TM in conjunction with a face-to-face component on improvements to the healing rate. The subgroup analyses showed a significant decrease in healing time with TM for venous ulcers or in conjunction with a face-to-face component. The subgroup analyses also indicated significant effects of TM with ≥ 2 types, for diabetes foot ulcers, in conjunction with a face-to-face component, or in combination with communication components in improving the amputation rate. Therefore, TM appears to be an effective method for chronic wound management. Clinical Trial: CRD42023462475


 Citation

Please cite as:

Zhang X, Guo Z, Duan Y, Sun C, Luo J

Effectiveness of Telemedicine on Wound-Related and Patient-Reported Outcomes in Patients With Chronic Wounds: Systematic Review and Meta-Analysis

JMIR Mhealth Uhealth 2025;13:e58553

DOI: 10.2196/58553

PMID: 40493508

PMCID: 12173094

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.