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Accepted for/Published in: JMIR Formative Research

Date Submitted: Mar 11, 2024
Date Accepted: Jan 8, 2025
Date Submitted to PubMed: Jan 10, 2025

The final, peer-reviewed published version of this preprint can be found here:

A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants

Breton Z, Stern E, Pinault M, Lhuillery D, Petit E, Panel P, Alexaline M

A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants

JMIR Form Res 2025;9:e58262

DOI: 10.2196/58262

PMID: 39791286

PMCID: 11909486

A digital program for daily life management with endometriosis: Pilot study on symptoms and quality of life among participants

  • Zélia Breton; 
  • Emilie Stern; 
  • Mathilde Pinault; 
  • Delphine Lhuillery; 
  • Erick Petit; 
  • Pierre Panel; 
  • Maïa Alexaline

ABSTRACT

Background:

After suffering for an average of 7 years before diagnosis, endometriosis patients are usually left with more questions than answers about managing their symptoms in the absence of a cure. To help women with endometriosis after their diagnosis, we developed an online support program available in France.

Objective:

This case-control study was designed to measure the impact of a digital health program on the quality of life and symptom levels of women with endometriosis.

Methods:

Ninety-two participants were included in the pilot study, among a total of 146 program participants who volunteered for this research. A control group of women with endometriosis who did not follow the program was recruited (n=404). Questionnaires assessing quality of life and symptoms levels were sent to program participants and controls at baseline and at three months. The control group was sampled according to initial pain level in order to obtain a similar pain profile between controls and program participants (n=149).

Results:

Perceived knowledge of endometriosis was significantly greater at three months among participants than in controls (P<.001). Participant’s quality of life evolution between baseline and three months improved and significantly differed from the control group for the core part of the EHP-5 (P=.03, small d) and the EQ-5D (P=.001, medium d). Over three months, global symptom burden, the general level of pain, anxiety, depression, dysmenorrhea, dysuria, chronic fatigue, neuropathic pain, and endobelly levels improved significantly among program participants. These improvements were significantly different from the control group for global symptom burden (P=.048, small d), anxiety (P<.001, medium d) and depression levels (P=.04, small d), neuropathic pain (P=.004, small d), and endobelly (P=.03, small d).

Conclusions:

The results from this pilot study suggest that a digital health program providing medical and scientific information about endometriosis and multidisciplinary self-management tools may be useful to reduce global symptom burden, anxiety, depression, neuropathic pain, and endobelly while improving knowledge on endometriosis and quality of life among participants.


 Citation

Please cite as:

Breton Z, Stern E, Pinault M, Lhuillery D, Petit E, Panel P, Alexaline M

A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants

JMIR Form Res 2025;9:e58262

DOI: 10.2196/58262

PMID: 39791286

PMCID: 11909486

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