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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jan 30, 2024
Open Peer Review Period: Jan 31, 2024 - Mar 27, 2024
Date Accepted: Feb 26, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Definitions and Measurements for Atypical Presentations at Risk for Diagnostic Errors in Internal Medicine: Protocol for a Scoping Review

Harada Y, Kawamura R, Yokose M, Shimizu T, Singh H

Definitions and Measurements for Atypical Presentations at Risk for Diagnostic Errors in Internal Medicine: Protocol for a Scoping Review

JMIR Res Protoc 2024;13:e56933

DOI: 10.2196/56933

PMID: 38526541

PMCID: 11002735

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Definitions and measurements for atypical presentations at risk for diagnostic errors in internal medicine: a scoping review protocol

  • Yukinori Harada; 
  • Ren Kawamura; 
  • Masashi Yokose; 
  • Taro Shimizu; 
  • Hardeep Singh

ABSTRACT

Background:

Atypical presentations have been increasingly recognized as a significant contributing factor to diagnostic errors in internal medicine. However, research to address associations of atypical presentations and diagnostic errors have not been well explored due to the lack of widely applicable definitions and criteria for what is considered an atypical presentation.

Objective:

To describe how atypical presentations are defined and measured in studies of diagnostic errors in internal medicine and use this new information to develop new criteria to identify atypical presentations at high risk for diagnostic errors.

Methods:

This scoping review will include research investigating the association between atypical presentations and diagnostic errors in the internal medicine setting. This study will follow an established framework for conducting scoping reviews. The data will be extracted through MEDLINE, Web of Science, CINAHL, Embase, The Cochrane Library, and Google Scholar searches. No limits will be applied to language, and articles indexed from database inception to December 31st, 2023 will be included. Two independent reviewers will conduct study selection and data extraction.

Results:

The extracted data will be presented in tabular format with descriptive statistics, and from this, the key components or types of atypical presentations—the purpose of this scoping review—will be identified to develop new criteria to identify atypical presentations for future studies of diagnostic errors. Developing the new criteria will follow a guidance for a basic qualitative content analysis with an inductive approach.

Conclusions:

This scoping review will provide the evidence summary to describe how atypical presentations are defined and measured in studies of diagnostic errors in internal medicine and develop new criteria to identify atypical presentations at high risk for diagnostic errors. Clinical Trial: doi:10.17605/OSF.IO/27D5M


 Citation

Please cite as:

Harada Y, Kawamura R, Yokose M, Shimizu T, Singh H

Definitions and Measurements for Atypical Presentations at Risk for Diagnostic Errors in Internal Medicine: Protocol for a Scoping Review

JMIR Res Protoc 2024;13:e56933

DOI: 10.2196/56933

PMID: 38526541

PMCID: 11002735

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