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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jan 15, 2024
Open Peer Review Period: Jan 15, 2024 - Mar 11, 2024
Date Accepted: May 27, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effects of Auditory and Visual White Noise on Oculomotor Inhibition in Children With Attention-Deficit/Hyperactivity Disorder: Protocol for a Crossover Study

Jostrup E, Nyström M, Tallberg P, Söderlund G, Gustafsson P, Claesdotter-Knutsson E

Effects of Auditory and Visual White Noise on Oculomotor Inhibition in Children With Attention-Deficit/Hyperactivity Disorder: Protocol for a Crossover Study

JMIR Res Protoc 2024;13:e56388

DOI: 10.2196/56388

PMID: 39146010

PMCID: 11362705

Effects of auditory and visual white noise on oculomotor inhibition in children with ADHD: Protocol for a crossover study

  • Erica Jostrup; 
  • Marcus Nyström; 
  • Pia Tallberg; 
  • Göran Söderlund; 
  • Peik Gustafsson; 
  • Emma Claesdotter-Knutsson

ABSTRACT

Background:

In attention-deficit/hyperactivity disorder (ADHD) poor inhibitory control is one of the main characteristics, with oculomotor inhibition impairments considered a potential biomarker of the disorder. While auditory white noise has demonstrated the ability to enhance working memory in this group, visual white noise is still unexplored and so are the effects of both types of white noise stimulation on oculomotor inhibition.

Objective:

This crossover study aims to explore the impact of auditory and visual white noise on oculomotor inhibition in children with ADHD and typically developing children (TDC). The study will investigate the impact of different noise levels (25% and 50% visual, 78 dB auditory) and performance will be evaluated both with and without noise stimulation. We hypothesize that exposure to white noise will improve performance in children with ADHD while impair performance for TDC.

Methods:

Memory Guided Saccades (MGS) and Prolonged Fixations (PF), known for their sensitivity in detecting oculomotor disinhibition in ADHD, will be used to assess performance. Children diagnosed with ADHD, withdrawing from medication for 24 hours, and TDC without psychiatric disorders will be recruited for the study.

Results:

Data collection was initiated in October 2023 and is expected to end February 2024. The first results are expected in March 2024.

Conclusions:

This study will examine whether cross-modal sensory stimulation can enhance executive function, specifically eye movement control, in children with ADHD. Additionally, the study will explore potential differences between auditory and visual noise effects in both groups. Our goal is to identify implications for understanding how noise can be used to improve cognitive performance. Clinical Trial: clinicaltrials.gov NCT06057441


 Citation

Please cite as:

Jostrup E, Nyström M, Tallberg P, Söderlund G, Gustafsson P, Claesdotter-Knutsson E

Effects of Auditory and Visual White Noise on Oculomotor Inhibition in Children With Attention-Deficit/Hyperactivity Disorder: Protocol for a Crossover Study

JMIR Res Protoc 2024;13:e56388

DOI: 10.2196/56388

PMID: 39146010

PMCID: 11362705

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