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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jan 15, 2024
Open Peer Review Period: Jan 15, 2024 - Mar 11, 2024
Date Accepted: Sep 16, 2024
Date Submitted to PubMed: Oct 25, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Leveraging Machine Learning to Identify Subgroups of Misclassified Patients in the Emergency Department: Multicenter Proof-of-Concept Study

Wyatt S, Lunde Markussen D, Haizoune M, Vestbø AS, Sima YT, Sandboe MI, Landschulze M, Bartsch H, Sauer CM

Leveraging Machine Learning to Identify Subgroups of Misclassified Patients in the Emergency Department: Multicenter Proof-of-Concept Study

J Med Internet Res 2024;26:e56382

DOI: 10.2196/56382

PMID: 39451101

PMCID: 11733519

Leveraging machine learning to identify subgroups of misclassified patients in the emergency department: a multi-center proof-of-concept study

  • Sage Wyatt; 
  • Dagfinn Lunde Markussen; 
  • Mounir Haizoune; 
  • Anders Strand Vestbø; 
  • Yeneabeba Tilahun Sima; 
  • Maria Ilene Sandboe; 
  • Marcus Landschulze; 
  • Hauke Bartsch; 
  • Christopher Martin Sauer

ABSTRACT

Background:

Hospitals use triage systems to prioritize the needs of patients within available resources. Misclassification of a patient can lead to either adverse outcomes in a patient who did not receive appropriate care in the case of undertriage or waste of hospital resources in the case of overtriage. Recent advances in machine learning algorithms allow for the quantification of variables important to under- and overtriage.

Objective:

The aim of this study was to identify clinical features most strongly associated with triage misclassification using a machine learning classification model to capture non-linear relationships.

Methods:

Multicenter retrospective cohort data from two big regional hospitals in Norway was extracted. The South African Triage system is used at Bergen University Hospital and the Rapid Emergency Triage and Treatment System is used at Trondheim University Hospital. Variables included triage score, age, gender, arrival time, subject area affiliation, reason for emergency department contact, discharge location, level of care, and time of death were retrieved. Random forest classification models were used to identify features with the strongest association with overtriage and undertriage in clinical practice in Bergen and Trondheim. We reported variable importance as SHAP-values (SHapley Additive exPlanations).

Results:

We collected data on 205,488 patient records from Bergen University Hospital and 304,997 patient records from Trondheim University Hospital. Overall, overtriage was very uncommon at both hospitals (all <0.1%), with undertriage differing between both location with 0.8% at Bergen and 0.2% at Trondheim University Hospital. Demographics were similar for both hospitals, however the percentage given a high priority triage score (red or orange) was higher in Bergen (24%) compared to 9% in Trondheim. Clinical referral department was found to be the variable with the strongest association with undertriage (mean SHAP +0.62 and +0.37 for Bergen and Trondheim, respectively).

Conclusions:

We identified subgroups of patients consistently undertriaged using two common triage systems. While the importance of clinical characteristics to triage misclassification varies by triage system and location, but we found consistent evidence between the two locations that clinical referral department is the most important variable associated with triage misclassification. Replication of this approach at other centers could help to further improve triage scoring systems and improve patient care worldwide.


 Citation

Please cite as:

Wyatt S, Lunde Markussen D, Haizoune M, Vestbø AS, Sima YT, Sandboe MI, Landschulze M, Bartsch H, Sauer CM

Leveraging Machine Learning to Identify Subgroups of Misclassified Patients in the Emergency Department: Multicenter Proof-of-Concept Study

J Med Internet Res 2024;26:e56382

DOI: 10.2196/56382

PMID: 39451101

PMCID: 11733519

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