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Accepted for/Published in: JMIR Biomedical Engineering

Date Submitted: Jan 10, 2024
Date Accepted: Mar 23, 2024

The final, peer-reviewed published version of this preprint can be found here:

Impact of Audio Data Compression on Feature Extraction for Vocal Biomarker Detection: Validation Study

Oreskovic J, Kaufman J, Fossat Y

Impact of Audio Data Compression on Feature Extraction for Vocal Biomarker Detection: Validation Study

JMIR Biomed Eng 2024;9:e56246

DOI: 10.2196/56246

PMID: 38875677

PMCID: 11058552

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Impact of Audio Data Compression on Feature Extraction for Vocal Biomarker Detection

  • Jessica Oreskovic; 
  • Jaycee Kaufman; 
  • Yan Fossat

ABSTRACT

Background:

Vocal biomarkers, derived from acoustic analysis of vocal characteristics, offer non-invasive avenues for medical screening, diagnostics, and monitoring. Previous research demonstrated the feasibility of predicting type 2 diabetes mellitus through acoustic analysis of smartphone-recorded speech. This study explores the impact of audio data compression on acoustic vocal biomarker development, critical for broader applicability in healthcare.

Objective:

The objective of this research is to analyze how common audio compression algorithms (MP3, M4A, WMA) at different bitrates, applied by distinct conversion tools (MediaHuman (MH), WonderShare (WS)), affect features crucial for vocal biomarker detection.

Methods:

Acoustic features were extracted from 17298 uncompressed voice samples recorded by 571 participants. Files were converted using MH and WS, applying MP3, M4A, and WMA at 128kbps and 320kbps. Feature extraction involved Python and Parselmouth. Non-parametric statistical analysis assessed the impact of compression on features.

Results:

Non-customizable differences in MH and WS encoders resulted in significant variations in compressed files. P values highlighted feature alterations, revealing feature-specific impacts of compression. Resilient features included meanF0, stdevF0, and rapJitter across various compression methods at specific bitrates. Compression effects were found to be feature-specific, with MH showing greater resilience. Some features were consistently affected, emphasizing the importance of understanding feature resilience for diagnostic applications. Healthcare implications suggest that certain features withstand compression, enabling medical use without compromising accuracy. Focused on specific features and formats, future research could broaden the scope to include diverse features, real-time compression algorithms, and various recording methods.

Conclusions:

This study enhances understanding of audio compression's influence on voice features and MFCCs, providing insights for developing applications across fields. The research underscores the significance of feature resilience in working with compressed audio data, laying a foundation for informed voice data utilization in evolving technological landscapes.


 Citation

Please cite as:

Oreskovic J, Kaufman J, Fossat Y

Impact of Audio Data Compression on Feature Extraction for Vocal Biomarker Detection: Validation Study

JMIR Biomed Eng 2024;9:e56246

DOI: 10.2196/56246

PMID: 38875677

PMCID: 11058552

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