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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Nov 28, 2023
Date Accepted: Feb 1, 2024

The final, peer-reviewed published version of this preprint can be found here:

Benefits, Harms, and Stakeholder Perspectives Regarding Opioid Therapy for Pain in Individuals With Metastatic Cancer: Protocol for a Descriptive Cohort Study

Jones K, White G, Bennett A, Bulls H, Escott P, Orris S, Escott E, Fischer S, Hamm M, Krishnamurti T, Wong R, LeBlanc TW, Liebschutz J, Meghani S, Smith C, Temel J, Ritchie C, Merlin J

Benefits, Harms, and Stakeholder Perspectives Regarding Opioid Therapy for Pain in Individuals With Metastatic Cancer: Protocol for a Descriptive Cohort Study

JMIR Res Protoc 2024;13:e54953

DOI: 10.2196/54953

PMID: 38478905

PMCID: 10973954

Benefits, harms, and stakeholder perspectives regarding opioid therapy for pain in individuals with metastatic cancer: A Protocol Paper

  • Katie Jones; 
  • Gretchen White; 
  • Antonia Bennett; 
  • Hailey Bulls; 
  • Paula Escott; 
  • Sarah Orris; 
  • Elizabeth Escott; 
  • Stacey Fischer; 
  • Megan Hamm; 
  • Tamar Krishnamurti; 
  • Risa Wong; 
  • Thomas W. LeBlanc; 
  • Jane Liebschutz; 
  • Salimah Meghani; 
  • Cardinale Smith; 
  • Jennifer Temel; 
  • Christine Ritchie; 
  • Jessica Merlin

ABSTRACT

Background:

Opioids are a key component of pain management among patients with metastatic cancer pain. However, the evidence base available to guide opioid-related decision-making in individuals with advanced cancer is limited.

Objective:

This manuscript outlines the protocol the “Opioid therapy for pain in individuals with metastatic cancer: The BEnefits, harms, and STakeholder perspectives (BEST) study”.

Methods:

This is a multicenter, prospective cohort study that aims to enroll 630 patients with advanced cancer, 20 care partners, and 20 clinicians (670 total participants).

Results:

The data collection is underway at four clinical sites and results will be reported in future manuscripts.

Conclusions:

Upon successful execution of our study protocol, we anticipate the development of a comprehensive evidence-base on opioid therapy in individuals with advanced cancer guided by the Behavioral Decision Research framework. Clinical Trial: N/a


 Citation

Please cite as:

Jones K, White G, Bennett A, Bulls H, Escott P, Orris S, Escott E, Fischer S, Hamm M, Krishnamurti T, Wong R, LeBlanc TW, Liebschutz J, Meghani S, Smith C, Temel J, Ritchie C, Merlin J

Benefits, Harms, and Stakeholder Perspectives Regarding Opioid Therapy for Pain in Individuals With Metastatic Cancer: Protocol for a Descriptive Cohort Study

JMIR Res Protoc 2024;13:e54953

DOI: 10.2196/54953

PMID: 38478905

PMCID: 10973954

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