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Accepted for/Published in: JMIR Human Factors

Date Submitted: Nov 20, 2023
Open Peer Review Period: Dec 19, 2023 - Feb 13, 2024
Date Accepted: Apr 22, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

A Multicomponent Intervention (POSSIBLE) to Improve Perceived Risk for HIV Among Black Sexual Minority Men: Feasibility and Preliminary Effectiveness Pilot Study

Dangerfield D II, Anderson JN, Wylie C, Bluthenthal R, Beyrer C, Farley JE

A Multicomponent Intervention (POSSIBLE) to Improve Perceived Risk for HIV Among Black Sexual Minority Men: Feasibility and Preliminary Effectiveness Pilot Study

JMIR Hum Factors 2024;11:e54739

DOI: 10.2196/54739

PMID: 38861707

PMCID: 11200034

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Feasibility and preliminary effectiveness of POSSIBLE: A multicomponent intervention to improve perceived risk for HIV among Black sexual minority men

  • Derek Dangerfield II; 
  • Janeane N. Anderson; 
  • Charleen Wylie; 
  • Ricky Bluthenthal; 
  • Chris Beyrer; 
  • Jason E. Farley

ABSTRACT

Background:

Increased pre-exposure prophylaxis (PrEP) use is urgently needed to substantially decrease HIV incidence among Black sexual minority men (SMM). Low perceived risk for HIV (PRH) is also a key unaddressed PrEP barrier for Black SMM. Peers and smartphone apps have are popular intervention tools to promote community health behaviors but few studies have utilized these in a multicomponent strategy. Therefore, we designed a multicomponent intervention called POSSIBLE that utilized an existing smartphone app called PrEPmeĀ® and a peer change agent (PCA) to increase PRH as a gateway to PrEP introduction. This paper describes the feasibility and preliminary effectiveness of POSSIBLE on PRH and willingness to accept a PrEP referral among Black SMM.

Objective:

This paper describes the feasibility and preliminary effectiveness of POSSIBLE on PRH and willingness to accept a PrEP referral among Black SMM.

Methods:

POSSIBLE was a theoretically guided, single group, pre-post pilot study conducted among Black SMM from Baltimore, MD between 2019 and 2021. POSSIBLE implemented a culturally congruent PCA and a mobile smartphone app called PrEPmeĀ® that allows users to self-monitor sexual risk behaviors and chat with the in-app community health worker to obtain PrEP service information. PRH was assessed using the 8-item PRH scale before and after baseline and follow-up study visits. At the end of each study visit, the PCA referred interested individuals to the CHW to learn more about PrEP service options.

Results:

A total 69 Black SMM participated, 80% of whom were retained for follow-up at month 1. The average age of participants was 32.5 years (range=19-62, [SD=8.1]). After baseline sessions, 42% participants were willing to be referred to PrEP services; 69% of them confirmed scheduled appointments with PrEP care teams. There were no statistically significant differences in PRH between baseline and follow-up visits (Table 3, t=-1.36; p=0.17).

Conclusions:

We observed no statistically significant improvement in PRH post-intervention. However, given the high retention rate, high acceptability, and strong participant satisfaction, POSSIBLE may be a feasible multicomponent strategy to implement among Black SMM. Future research should test a statistically powered peer-based approach on PrEP initiation among Black SMM. Clinical Trial: NCT04533386


 Citation

Please cite as:

Dangerfield D II, Anderson JN, Wylie C, Bluthenthal R, Beyrer C, Farley JE

A Multicomponent Intervention (POSSIBLE) to Improve Perceived Risk for HIV Among Black Sexual Minority Men: Feasibility and Preliminary Effectiveness Pilot Study

JMIR Hum Factors 2024;11:e54739

DOI: 10.2196/54739

PMID: 38861707

PMCID: 11200034

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