Accepted for/Published in: JMIR Public Health and Surveillance
Date Submitted: Oct 23, 2023
Open Peer Review Period: Oct 22, 2023 - Nov 5, 2023
Date Accepted: May 8, 2024
(closed for review but you can still tweet)
Congenital anomalies mortality in children under 5 years in Eastern China: a descriptive study based on surveillance data from 2012 to 2021
ABSTRACT
Background:
As one of the leading causes of child mortality, congenital anomalies (CAs) deaths has been a prominent obstacle on meeting the Sustainable Developmental Goals (SDG) 3.2.
Objective:
To understand the death burden and trends of under-five-CA-mortality (CAMR) in Zhejiang, a province with the best medical services and public health foundations at Eastern China, we hereby perform this study.
Methods:
We used data retrieved from the under-5-mortality surveillance system in Zhejiang from 2012-2021. CAMR by sex, residence and age groups by year was calculated. Poisson regression models were used to estimate annual average change rate of CAMR and to obtain the rate ratio between subgroups after adjusting for sex, residence and age groups when appropriate.
Results:
The CAMR declined from 121.9 per 100 000 live births in 2012 to 62.5 in 2021, with a 9.0% (95% CI=7.2%~10.7%) annually average decline rate. The declining trend was also observed in both sex, rural and urban and all age groups except children aged 1-4 years. Among all CA subtypes, circulatory system malformations, mainly congenital heart diseases, accounts for over 50% of all CA deaths and ranks 1st across all years. Chromosomal abnormalities deaths, though insignificant (P>0.05), tends to grow in recent years.
Conclusions:
Despite of the remarkable achievements that has been made, we still face great challenges to fulfill SDG 3.2. Therefore, future researches and practices should focus more on the prevention of CAs incidence and long-term management protocol to improve the survival chances of children born with CAs. Clinical Trial: Not Applicable
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