Previously submitted to: Interactive Journal of Medical Research (no longer under consideration since Oct 22, 2024)
Date Submitted: Oct 8, 2023
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Endoscopic Balloon Dilatation for Pediatric Subglottic Stenosis: A Meta-Analysis of Successful Outcomes
ABSTRACT
Background:
Pediatric subglottic stenosis (SGS) sometimes develops abruptly and needs rapid treatment. Endoscopic balloon dilation (EBD) is a novel method for treating children with SGS endoscopically.
Objective:
The primary goal of this study was to systematically identify all relevant published articles on the use of primary endoscopic balloon dilation for the management of pediatric patients with subglottic stenosis, critically assess the technique's success, and determine which patients are the best candidates for the procedure.
Methods:
This was a systematic review and meta-analysis that aimed to investigate the use and success rate of EBD for treating pediatric SGS. An electronic systematic literature search of three major databases,PubMed, EBSCO, and Web of Science&MEDLINE through Clarivate,was conducted to include the eligible articles.
Results:
A total of 14 unique studies were included in the final analysis, with 473 cases of pediatric SGS. The pooled success rate of EBD in treatment of pediatric SGS was 76% (k = 14 studies, 95% confidence interval [CI] = 0.65-0.86, P <.001, Q test for heterogeneity = 0.03, P <.001, I2 = 91%).
Conclusions:
We reported a high success rate of EBD in treating pediatric SGS. The reported complications were uncommon, although they can be serious and life-threatening. The intensity of SGS may be related to the likelihood of therapy failure.
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