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Accepted for/Published in: JMIR Cancer

Date Submitted: Sep 10, 2023
Date Accepted: Nov 28, 2024

The final, peer-reviewed published version of this preprint can be found here:

The Impact of Digital Inequities on Nasal and Paranasal-Sinus Cancer Disparities in the United States: A Cohort Study

Fei-Zhang DJ, Lawrence AS, Chelius DC, Sheyn AM, Rastatter JC

The Impact of Digital Inequities on Nasal and Paranasal-Sinus Cancer Disparities in the United States: A Cohort Study

JMIR Cancer 2025;11:e52627

DOI: 10.2196/52627

PMID: 40663723

PMCID: 12282939

The Impact of Digital Inequities on Nasal and Paranasal Sinus Cancer Disparities in the United States: A Cohort Study

  • David J. Fei-Zhang; 
  • Amelia Sherron Lawrence; 
  • Daniel C. Chelius; 
  • Anthony M. Sheyn; 
  • Jeffrey C. Rastatter

ABSTRACT

Background:

In the modern era, the use of technology can substantially impact care access. However, the association of “digital inequities” with nasal and paranasal-sinus cancer (NPSC) outcomes remains seldom-studied.

Objective:

To utilize the Digital Inequity Index (DII), a novel, comprehensive tool that quantifies digital resource access, to assess its impact on NPSC disparities in the US.

Methods:

8,012 NPSC patients from 2008-2017 in SEER were assessed for significant regression trends in long-term follow-up period and treatment receipt across NPSCs with increasing overall digital inequity, as measured by DII. DII was based on 17 census-tract level variables derived from the US Census and Federal Communications Commission. Variables were categorized as infrastructure-access (i.e. electronic device ownership, internet provider availability, income-broadband subscription ratio) or sociodemographic (education, income, age, disability), ranked, and then averaged into a composite score.

Results:

With increasing digital inequity, significant decreases in length of long-term follow-up were observed with nasopharyngeal (p<0.001) and maxillary sinus cancers (p=0.022), with decreases as high as 19% (35.2 to 28.5 months, nasopharynx). Electronic device and service availability inequities showcased higher-magnitude contributions to observed associated regression trends while income-broadband ratio contributed less. Significantly decreased odds of receiving indicated surgery and radiation for several NPSCs were also observed.

Conclusions:

Digital inequities contribute to detrimental NPSC-care trends in the US. This should prompt discussion of strategies to alleviate disparities while contextualizing national sociodemographics of online access. Clinical Trial: N/A


 Citation

Please cite as:

Fei-Zhang DJ, Lawrence AS, Chelius DC, Sheyn AM, Rastatter JC

The Impact of Digital Inequities on Nasal and Paranasal-Sinus Cancer Disparities in the United States: A Cohort Study

JMIR Cancer 2025;11:e52627

DOI: 10.2196/52627

PMID: 40663723

PMCID: 12282939

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.