Accepted for/Published in: Interactive Journal of Medical Research
Date Submitted: Aug 24, 2023
Open Peer Review Period: Aug 9, 2023 - Oct 4, 2023
Date Accepted: Jun 21, 2024
(closed for review but you can still tweet)
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Process evaluations of interventions for the prevention of Type 2 diabetes in women with gestational diabetes mellitus: a systematic review
ABSTRACT
Background:
Women with gestational diabetes mellitus (GDM) have an increased risk of developing type 2 diabetes mellitus (T2DM) later in life. Whilst diabetes prevention interventions (DPI) have been developed to delay or prevent the onset of T2DM, few studies have provided process evaluation (PE) data to assess the mechanisms of impact, quality of implementation or contextual factors that may influence the effectiveness of the intervention in practice. The aim of this review was to identify and evaluate PE data and how these link to outcomes of randomised control trials of T2DM prevention interventions for women with GDM.
Objective:
Specific objectives were to identify the extent to which PE components were reported and described in RCTs of DPIs for women with previous or current GDM and to assess whether these components could contribute to explaining the intervention outcomes of the DPIs.
Methods:
A systematic review was conducted to identify studies published from 2005–2020. Five electronic bibliographic databases (Cochrane Library, Cochrane Collaboration Registry of Controlled Trials, EMBASE, PubMed, and MEDLINE) were searched using the Medical Research Council’s PE framework of complex interventions to identify key PE components.
Results:
Twenty-four studies were included. Only five explicitly reported a PE theoretical framework. Whilst most studies linked PE data with study outcomes, it was unclear which of the reported PE components were specifically linked to the positive outcomes.
Conclusions:
We need clearer guidance and robust frameworks for conducting PEs for the development and reporting of DPIs for women with GDM.
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.