Accepted for/Published in: JMIR Research Protocols
Date Submitted: Jun 27, 2023
Open Peer Review Period: Jun 27, 2023 - Aug 22, 2023
Date Accepted: Dec 7, 2023
(closed for review but you can still tweet)
Blockchain-Based Dynamic Consent: Protocol for an Integrative Review of Applications for Patient-Centric Research and Health Information Sharing
ABSTRACT
Background:
Blockchain has been proposed as a key technology to share health information and facilitate a shift towards more patient-centric research and decision-making. For instance, blockchain-based dynamic consent has been suggested as a potential solution to consent challenges encountered in longitudinal research and research repositories. However, blockchain-based dynamic consent is a relatively new concept, and it is not yet clear how well the suggested implementations will work in practice. While some studies and pilot projects explore blockchain technology in dynamic consent, there is no consensus on whether this technology can be effectively utilized with health or research data.
Objective:
To review current literature to identify implementations of blockchain-based dynamic consent, the impact of this technology within clinical settings, and to establish best practices for future research and implementations.
Methods:
This objective will be addressed using methods of integrative review. The PRISMA-P criteria were utilized as a basic framework to guide the review's structure and nature of reporting. The literature search will include six online scientific databases to identify papers explicitly addressing the design and implementation of blockchain-based dynamic consent solutions. The quality of studies will be appraised, and data will be extracted to identify themes.
Results:
This study will document evidence of effectiveness, efficiencies, and/or satisfaction with blockchain and dynamic consent technology used for health information. Several elements will also be collected about the implementation/commercialization stage, regulatory compliance, usability, and methods of managing identity.
Conclusions:
This review aims to provide a comprehensive understanding of the progress of emerging blockchain-based dynamic consent solutions and the rigor with which implementations and prospective benefits are assessed. This literature review is expected to identify optimal approaches to implementing and studying the effectiveness of blockchain-based dynamic consent technologies. Clinical Trial: This protocol was registered with PROSPERO 2023 CRD42023396983, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023396983
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Copyright
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