Accepted for/Published in: JMIR Public Health and Surveillance
Date Submitted: Jun 19, 2023
Open Peer Review Period: Jun 19, 2023 - Jul 3, 2023
Date Accepted: Oct 3, 2023
(closed for review but you can still tweet)
Burden and Trends of Urticaria Globally, Regionally, and Nationally from 1990 to 2019 : A Systematic Analysis
ABSTRACT
Background:
Urticaria, a prevalent dermatological condition marked by itchy, red welts, negatively impacts quality of life. The comprehensive understanding of urticaria's worldwide epidemiology is critical for effective public health initiatives.
Objective:
To scrutinize the global, regional, and national burden of urticaria and its trends by age, sex, and Socio-demographic Index (SDI) from 1990 to 2019 using data from the Global Burden of Disease (GBD) study.
Methods:
We conducted a systematic analysis using data from the 2019 GBD study. The prevalence, incidence, and Disability-Adjusted Life Years (DALYs) of urticaria were estimated using the DisMod-MR 2.1, a Bayesian meta-regression tool. The global burden was assessed across global, SDI areas, 21 regions and 204 countries from 1990 to 2019.
Results:
Between 1990 and 2019, the global age-standardized prevalence, incidence, and DALY rates of urticaria remained stable. In 2019, an estimated 65.14 million people worldwide had urticaria, with a prevalence of 841.88 per 100,000 cases. The age-standardized DALY rate was 50.39 per 100,000 cases, with a slight increase from 1990's rate. Females had consistently higher rates than males. Regions with low-middle SDI had the highest age-standardized prevalence, incidence, and DALY rates, whereas high SDI regions had the lowest. Central Europe presented the highest rates, while Western Europe had the lowest in 2019. Nationally, substantial variation existed, with the highest prevalence in Nepal and the lowest in Portugal. The greatest burden in numbers of DALYs was in India, followed by China, and Pakistan. Rates were highest in younger age groups and females.
Conclusions:
Urticaria remains a significant global health issue, with considerable variation across regions and countries. The increased burden among females, the rising burden in younger populations, and the regional differences in disease burden call for tailored interventions and policies to tackle this emerging public health issue.
Citation
Per the author's request the PDF is not available.
Copyright
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