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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Apr 25, 2023
Open Peer Review Period: Apr 25, 2023 - Jun 20, 2023
Date Accepted: Jun 28, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

A Universal Digital Stress Management Intervention for Employees: Randomized Controlled Trial with Health-Economic Evaluation

Freund J, Smit F, Lehr D, Zarski AC, Berking M, Riper H, Funk B, Ebert DD, Buntrock C

A Universal Digital Stress Management Intervention for Employees: Randomized Controlled Trial with Health-Economic Evaluation

J Med Internet Res 2024;26:e48481

DOI: 10.2196/48481

PMID: 39437382

PMCID: 11538874

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Health-economic Evaluation of a Universal Digital Stress Management Intervention for Employees Alongside a Randomized Controlled Trial

  • Johanna Freund; 
  • Filip Smit; 
  • Dirk Lehr; 
  • Anna-Carlotta Zarski; 
  • Matthias Berking; 
  • Heleen Riper; 
  • Burkhardt Funk; 
  • David Daniel Ebert; 
  • Claudia Buntrock

ABSTRACT

Background:

Stress is highly prevalent and known to be a risk factor for a wide range of physical and mental disorders. The effectiveness of digital stress management interventions has been confirmed; however, research on its economic merits is still limited.

Objective:

To assess the cost-effectiveness, cost–utility, and cost-benefit of a universal digital stress management intervention for employees compared to a waitlist control condition within a time horizon of 6 months.

Methods:

Recruitment was directed at the German working population. A sample of 396 employees was randomly assigned to the intervention group (n = 198) or the waiting list control (WLC) group (n = 198). The digital stress management intervention included seven sessions plus one booster session and was offered without therapeutic guidance. Health service use, patient and family expenditures, and productivity losses were self-assessed and used for costing from a societal and an employer’s perspective. Costs were related to symptom-free status (PSS-10 score 2 standard deviations below the study population baseline mean) and quality-adjusted life years (QALYs) gained. Sampling error was handled using nonparametric bootstrapping.

Results:

From a societal perspective, the digital intervention had a 56% (55%) probability of being cost-effective at a willingness-to-pay of €0 per symptom-free person (QALY) gained, compared to WLC. This probability increased to 80% at a societal willingness-to-pay of €20,000 per QALY gained. Taking the employer’s perspective, the digital intervention showed a probability for a positive return on investment of 78%.

Conclusions:

Digital preventive stress management for employees appears to be cost-effective societally and provides a favorable return-on-investment for employers. Clinical Trial: German clinical trials register (DRKS00005699)


 Citation

Please cite as:

Freund J, Smit F, Lehr D, Zarski AC, Berking M, Riper H, Funk B, Ebert DD, Buntrock C

A Universal Digital Stress Management Intervention for Employees: Randomized Controlled Trial with Health-Economic Evaluation

J Med Internet Res 2024;26:e48481

DOI: 10.2196/48481

PMID: 39437382

PMCID: 11538874

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