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Accepted for/Published in: JMIR Research Protocols

Date Submitted: May 2, 2023
Open Peer Review Period: Apr 18, 2023 - Jun 13, 2023
Date Accepted: Dec 8, 2023
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Web-Based Intervention to Act for Weight Loss in Adults With Type 2 Diabetes With Obesity (Chance2Act): Protocol for a Nonrandomized Controlled Trial

Mohamad M, Mohd Saad N, Mat Ruzlin AN

Web-Based Intervention to Act for Weight Loss in Adults With Type 2 Diabetes With Obesity (Chance2Act): Protocol for a Nonrandomized Controlled Trial

JMIR Res Protoc 2024;13:e48313

DOI: 10.2196/48313

PMID: 38294848

PMCID: 10867745

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Effectiveness of a web-based intervention based on the Transtheoretical Model to act for weight loss for type 2 diabetes adults with obesity: protocol for a quasi-experimental study

  • Mariam Mohamad; 
  • Noraini Mohd Saad; 
  • Aimi Nadira Mat Ruzlin

ABSTRACT

Background:

In type 2 diabetes (T2D) adults, weight loss can improve hemoglobin A1c, blood pressure, triglycerides, quality of life, and reduce the frequency of medications needed. Unfortunately, there is a large proportion of T2D adults who are not ready to change for weight loss. Over decades, web-based health technologies are increasingly used as a delivery mode for health promotion and prevention for obesity. However, evidence of their effectiveness for initializing and maintaining healthy behavior, particularly among T2D adults, is still scarce.

Objective:

This study aims to develop, validate, and determine the effectiveness of a web-based intervention called “Chance2Act” among T2D adults with obesity to act for weight loss.

Methods:

A web-based intervention will be developed based on the Transtheoretical Model targeting T2D adults with obesity who are not ready to change for weight loss. Phase 1 will involve the development and validation of the web-based health intervention module. In phase 2, a quasi-experimental study will be conducted in two government health clinics selected by the investigator. This is an unblinded study with a parallel assignment (i.e. intervention vs. control (usual care) with an allocation ratio of 1:1). 124 study participants will be recruited, of which 62 participants will receive the Chance2Act intervention in addition to the usual care. The primary outcome is the changes of the stages of change to lose weight. The secondary outcomes include changes in self-efficacy, decisional balance, family support for weight loss, BMI, waist circumference, and body fat composition.

Results:

We hypothesize that the Chance2Act intervention will elicit significant behavioral changes for weight loss among the participants (i.e. readiness to change, self-efficacy, and decisional balance), cause meaningful improvement in family support for weight loss, and significantly reduce the BMI as well as the body fat composition among the participants.

Conclusions:

The Chance2Act intervention is expected to yield new knowledge on the effects of a theory-based digital intervention targeting behavior change from an individual perspective. It is hoped that the evidence obtained from this study will enhance the delivery of obesity care among T2D adults in primary care settings. Clinical Trial: U.S. Clinical Trial Register NCT05736536; https://beta.clinicaltrials.gov/study/NCT05736536


 Citation

Please cite as:

Mohamad M, Mohd Saad N, Mat Ruzlin AN

Web-Based Intervention to Act for Weight Loss in Adults With Type 2 Diabetes With Obesity (Chance2Act): Protocol for a Nonrandomized Controlled Trial

JMIR Res Protoc 2024;13:e48313

DOI: 10.2196/48313

PMID: 38294848

PMCID: 10867745

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