Accepted for/Published in: JMIR Research Protocols
Date Submitted: Apr 16, 2023
Date Accepted: Jun 27, 2023
The effects of cognitive interventions in individuals with chronic respiratory diseases: a protocol for a systematic review
ABSTRACT
Background:
Chronic respiratory diseases (CRD) may cause reduced oxygen availability to organs and body tissues, leading to an increased risk for ischemic damage, which can result in brain tissue injury. This damage can lead to a myriad of neurological symptoms contributing to cognitive decline. Cognitive training may attenuate the cognitive deficits in people with CRD, however, its effects have not yet been systematically summarized in the literature.
Objective:
The purpose of this systematic review is to assess the effects of cognitive training on cognitive function (primary outcome), health-related quality of life, self-management, symptoms, physical activity, physical function, ability to complete activities of daily living, and hospital admissions in individuals with CRD.
Methods:
This review will be conducted according to the Cochrane Handbook for systematic reviews of interventions and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline. Searches will be performed in MEDLINE, Embase, Emcare, PsycINFO, Scopus, and CINAHL. Articles will be included if exploring the effects of cognitive training on adults with CRD, published in a peer-reviewed journal and written in English, French, or Portuguese. Risk of bias will be evaluated with the Cochrane Risk of Bias 2 tool for randomized controlled trials (RoB-2), and the Risk Of Bias In Non-randomized Studies of Interventions (ROBINS-I) for non-randomized studies. Meta-analyses will be performed if at least two studies provided sufficient data for a specific outcome. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) assessment will be used to evaluate the overall quality of the evidence.
Results:
This systematic review was initiated in November 2022 and registered with PROSPERO in February 2023, prior to title and abstract screening. Full-text screening of articles will be completed in May 2023 and to date, 5 articles met the inclusion criteria and will be included in the systematic review. Data extraction and drafting of the manuscript will occur from May 2023 to August 2023, with expected publication in February 2024.
Conclusions:
This systematic review will be the first to evaluate the effects of cognitive training for people with CRD. Its results will inform clinical practice on the use of cognitive training for CRD but also further needed research on this field. Clinical Trial: PROSPERO CRD42023396234; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023396234
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