Accepted for/Published in: JMIR mHealth and uHealth
Date Submitted: Mar 22, 2023
Date Accepted: Dec 20, 2023
Effectiveness of a nurse-led mobile-based health coaching program for prostate cancer patients at high risk of metabolic syndrome: A randomized wait-listed controlled trial
ABSTRACT
Background:
Androgen deprivation therapy (ADT), used as standard treatment for prostate cancer (PC), causes many physical side effects. In particular, it causes metabolic changes, such as fasting glucose abnormalities or accumulation of body fat, and its continuation can lead to metabolic syndrome (MetS), which is closely related to diabetes or cardiovascular disease. Therefore, it is important to maintain and practice a healthy lifestyle in patients with PC.
Objective:
To evaluate the effectiveness of a nurse-led online program that aims to promote a healthy lifestyle for patients with prostate cancer undergoing androgen deprivation therapy with metabolic syndrome risk factors.
Methods:
A single-blind randomized controlled trial study was conducted in South Korea. A total of 48 patients were randomly assigned to experimental and control groups. The inclusion criteria were patients who had undergone androgen deprivation therapy for more than six months, had at least one of the metabolic syndrome components in the abnormal range, and could access an online education program. The experimental group attended the 4-week online program on exercise and diet that included counseling and encouragement for maintaining a healthy lifestyle. The control group received an informational pamphlet at the end of the study. The main outcomes were lifestyle, metabolic syndrome components, body composition, and health-related quality of life. A linear mixed model was used for the statistical analysis.
Results:
The experimental group showed more positive changes in a healthy lifestyle (B=29.23, <.001), metabolic syndrome components (fasting blood sugar: B=-12.0, p=0.05; abdominal circumference: B=-2.49, p=0.04), body composition (body weight: B=-1.52, p<.001; body mass index: B=-0.55, p<.001), and the urinary irritative/obstructive domain of health-related quality of life (B=14.63, p=0.00) over time than the control group.
Conclusions:
Lifestyle changes through nurse-led education can improve the components of metabolic syndrome, body composition, and ADT side effects. Nurses can induce positive changes in patients’ lifestyles and improve the self-management of patients starting androgen deprivation therapy through this program. Clinical Trial: Clinical Research Information Service, CRIS registration (No. KCT0006560)
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