Accepted for/Published in: JMIR Public Health and Surveillance
Date Submitted: Feb 4, 2023
Date Accepted: Jun 15, 2023
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Association Between Loss of Gait Harmony and Cognitive Impairment: Cross-sectional Study
ABSTRACT
Background:
Functional limitations and disabilities have been associated with a decrease in cognitive function with increasing age. Gait performance and cognitive function have been associated with gait variability in executive function, the phase domain in memory, and gait abnormalities in cognitive decline.
Objective:
We aimed to investigate whether gait harmony was associated with cognitive function, and to explore of each cognitive function in a specific harmonic state.
Methods:
The study population was 510 aged ≥60 years of age who visited the Department of Neurology at Veterans Health Service Medical Center. Gait data were collected using a three-dimensional motion capture equipment with a wireless inertial measurement unit system. For cognitive function assessments, we used the Seoul Neuropsychological Screening Battery-Core (SNSB-C) test.
Results:
In general, the association between the SNSB-C tests and the stance/swing ratio in the >1.63 ratio group yielded lower beta coefficients than those in the 1.50-1.63 ratio group. After adjustment for confounders, odds ratio for the Digit Symbol Coding and the Korean version of Color Word Stroop Test: 60seconds for frontal and executive function was significantly lower for the >1.63 ratio group than the reference group.
Conclusions:
Our findings suggest that the gait phase ratio may be a valuable indicator of cognitive impairment.
Citation
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