Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jan 2, 2023
Date Accepted: Jun 9, 2023
Date Submitted to PubMed: Jul 25, 2023

The final, peer-reviewed published version of this preprint can be found here:

Benefits of Telerehabilitation for Patients With Severe Acquired Brain Injury: Promising Results From a Multicenter Randomized Controlled Trial Using Nonimmersive Virtual Reality

Calabrò RS, Bonanno M, Torregrossa W, Cacciante L, Celesti A, Rifici C, Tonin P, De Luca R, Quartarone A

Benefits of Telerehabilitation for Patients With Severe Acquired Brain Injury: Promising Results From a Multicenter Randomized Controlled Trial Using Nonimmersive Virtual Reality

J Med Internet Res 2023;25:e45458

DOI: 10.2196/45458

PMID: 37490017

PMCID: 10477931

Do patients with severe acquired brain injury benefit from Telerehabilitation? Promising results from a multicentric randomised controlled trial using non-immersive virtual Reality. 

  • Rocco Salvatore Calabrò; 
  • Mirjam Bonanno; 
  • William Torregrossa; 
  • Luisa Cacciante; 
  • Antonio Celesti; 
  • Carmela Rifici; 
  • Paolo Tonin; 
  • Rosaria De Luca; 
  • Angelo Quartarone

ABSTRACT

Background:

In neurorehabilitation the use of innovative technologies offers many opportunities to monitor and to improve the health status of patients with acquired brain injury (SABI) patients. Telerehabilitation allows for continuity of service through the entire rehabilitation cycle including assessment, intervention, consultation and education, affording early reintegration and positively enhancing quality of life.

Objective:

The main purpose of this multicenter randomised control trial was to test the effect of an advanced training with a virtual reality rehabilitation system (i.e., the VRRS-Home-Kit device) in improving functional outcomes in patients affected by SABI.

Methods:

Forty SABI patients and their caregivers attending two Italian rehabilitation Centres, were enrolled in the study protocol and randomised in two groups. Twenty patients received the experimental training using the VRRS-HomeKit (Tele-Neuro VRRS) whereas the other twenty were submitted to usual territorial rehabilitative treatments (UTRT).

Results:

The experimental group achieved a statistically significant improvement concerning both general and motor outcomes, as well as psychological well-being and quality of life, as compared to the control group. In particular, Barthel Index (p <0.0001), Frontal Assessment Battery (p <0.0001), and Beck Depression Inventory (p <0.0001) were the outcome scales with the best improvement. The burden of caregivers also significantly improved in the Teleneuro-VRRS group (CBI, p <0.0004).

Conclusions:

Our results suggest that VRRS is a suitable alternative and/or complementary tool to improve functional outcomes and reduce levels of anxiety and depression symptoms in SABI patients with a reduction of caregivers’ burden distress Clinical Trial: RCT (NCT03709875) registered on clinicaltrial.com


 Citation

Please cite as:

Calabrò RS, Bonanno M, Torregrossa W, Cacciante L, Celesti A, Rifici C, Tonin P, De Luca R, Quartarone A

Benefits of Telerehabilitation for Patients With Severe Acquired Brain Injury: Promising Results From a Multicenter Randomized Controlled Trial Using Nonimmersive Virtual Reality

J Med Internet Res 2023;25:e45458

DOI: 10.2196/45458

PMID: 37490017

PMCID: 10477931

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.